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4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt , CAS No.92921-24-9

Item Number
M123456
Grouped product items
SKUSizeAvailabilityPrice Qty
M123456-25mg
25mg
In stock
$105.90
M123456-100mg
100mg
In stock
$293.90
M123456-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$577.90
M123456-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$925.90
M123456-1g
1g
In stock
$1,479.90
M123456-5g
5g
In stock
$5,919.90

Amine-to-sulfhydryl crosslinking agent

Basic Description

SynonymsSulfo-SMCC|92921-24-9|Sulfo-SMCC sodium|Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate|Sulfo-SMCC (sodium)|Sulfo-SMCC Crosslinker|HH32D7TN36|sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrr
Biochemical and Physiological Mechanisms4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt is known to introduce a well-defined number of maleimide groups into the protein which confers them a long shelf-life at low temperatures and can be further
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt (sulfoSMCC) is a heterobifunctional protein/peptide cross-linker and a suitable cross-coupling reagent.

Names and Identifiers

IUPAC Name sodium;1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
INCHI InChI=1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1
InChi Key VUFNRPJNRFOTGK-UHFFFAOYSA-M
Canonical SMILES C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
Isomeric SMILES C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
WGK Germany 3
PubChem CID 4618794
Molecular Weight 436.37

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

12 results found

Lot NumberCertificate TypeDateItem
A2303379Certificate of AnalysisJun 14, 2022 M123456
A2431241Certificate of AnalysisJun 14, 2022 M123456
C2419207Certificate of AnalysisJun 14, 2022 M123456
G2220598Certificate of AnalysisJun 14, 2022 M123456
G2220601Certificate of AnalysisJun 14, 2022 M123456
G2220663Certificate of AnalysisJun 14, 2022 M123456
G2220668Certificate of AnalysisJun 14, 2022 M123456
G2220669Certificate of AnalysisJun 14, 2022 M123456
G2311038Certificate of AnalysisJun 14, 2022 M123456
H2325051Certificate of AnalysisJun 14, 2022 M123456
K2221157Certificate of AnalysisJun 14, 2022 M123456
L2307159Certificate of AnalysisJun 14, 2022 M123456

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Chemical and Physical Properties

Solubilitysoluble in water (2.5 mg/ml) and DMF
Sensitivityheat & Moisture sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

References

1. Li B et al..  (2021)  Molecularly engineered truncated tissue factor with therapeutic aptamers for tumor-targeted delivery and vascular infarction..  Acta Pharm Sin B,  11  (7): (2059-2069).  [PMID:34386338]

Solution Calculators