4-Phenylpyridine - 97%, high purity , CAS No.939-23-1

  • ≥97%
Item Number
P117997
Grouped product items
SKUSizeAvailabilityPrice Qty
P117997-200mg
200mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
P117997-1g
1g
In stock
$13.90
P117997-5g
5g
In stock
$51.90
P117997-25g
25g
In stock
$146.90
P117997-100g
100g
In stock
$526.90

Basic Description

Synonyms5SH | DTXSID5022140 | p-Phenylpyridine | SMR000112292 | AC-5099 | Q27258800 | NSC70375 | NSC-70375 | NCGC00247406-01 | NSC77935 | NSC-77935 | Pyridine, phenyl- | 4-PHENYLPYRIDINE | 4-Phenyl-pyridine | BRN 0110490 | EN300-49165 | SCHEMBL19003057 | 5-20-07-
Specifications & Purity≥97%
Storage TempArgon charged
Shipped InNormal

Associated Targets(Human)

QDPR Tchem Dihydropteridine reductase (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
BRPF1 Tchem Peregrin (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GNAS Tbio Protein ALEX (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
IDO1 Tchem Indoleamine 2,3-dioxygenase 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Stromelysin-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDO1 Tchem Indoleamine 2,3-dioxygenase (6650 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Qdpr Dihydropteridine reductase (31 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
bla OXA-48 (65 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488181881
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488181881
IUPAC Name 4-phenylpyridine
INCHI InChI=1S/C11H9N/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-9H
InChi Key JVZRCNQLWOELDU-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=CC=NC=C2
Isomeric SMILES C1=CC=C(C=C1)C2=CC=NC=C2
WGK Germany 3
RTECS UT7141000
PubChem CID 13651
Molecular Weight 155.2
Beilstein 110490
Reaxy-Rn 110490

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

15 results found

Lot NumberCertificate TypeDateItem
A2408757Certificate of AnalysisDec 01, 2023 P117997
A2408758Certificate of AnalysisDec 01, 2023 P117997
A2408759Certificate of AnalysisDec 01, 2023 P117997
A2408760Certificate of AnalysisDec 01, 2023 P117997
L1916163Certificate of AnalysisOct 20, 2023 P117997
G23181001Certificate of AnalysisJun 26, 2023 P117997
G23181012Certificate of AnalysisJun 26, 2023 P117997
G23181140Certificate of AnalysisJun 26, 2023 P117997
G23181143Certificate of AnalysisJun 26, 2023 P117997
G23181146Certificate of AnalysisJun 26, 2023 P117997
G23181147Certificate of AnalysisJun 26, 2023 P117997
G23181158Certificate of AnalysisJun 26, 2023 P117997
I2226226Certificate of AnalysisSep 28, 2022 P117997
C2222013Certificate of AnalysisMar 25, 2022 P117997
C2222015Certificate of AnalysisMar 24, 2022 P117997

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Chemical and Physical Properties

SolubilitySolubility in water: Insoluble in cold water; Solubility in other solvents: Soluble in ethanol and ethyl ether;Solubility in Methanol almost transparency;
SensitivityAir sensitive
Boil Point(°C)274-275°C
Melt Point(°C)69-73°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
RTECS UT7141000
Reaxy-Rn 110490

Related Documents

Alternative Products

Citations of This Product

1. Chao Liu, Lei Shi, Jiaxu Zhang, Jianmin Sun.  (2022)  One-pot synthesis of pyridine-based ionic hyper-cross-linked polymers with hierarchical pores for efficient CO2 capture and catalytic conversion.  CHEMICAL ENGINEERING JOURNAL,  427  (131633).  [PMID:] [10.1016/j.cej.2021.131633]
2. Xin Xiao, Shunheng Tu, Chunxia Zheng, Huan Zhong, Xiaoxi Zuo, Junmin Nan.  (2015)  L-Asparagine-assisted synthesis of flower-like β-Bi2O3 and its photocatalytic performance for the degradation of 4-phenylphenol under visible-light irradiation.  RSC Advances,  (91): (74977-74985).  [PMID:] [10.1039/C5RA13985F]

References

1. M N Hassan,J H Thakar,J D Grimes.  (1990-01-01)  Behavioral and biochemical effects of 4-phenylpyridine, 2-phenylpyridine, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rodents..  Advances in neurology,  53  (219-223).  [PMID:2239461]
2. R R Ramsay,K A McKeown,E A Johnson,R G Booth,T P Singer.  (1987-07-15)  Inhibition of NADH oxidation by pyridine derivatives..  Biochemical and biophysical research communications,  146  ((1)): (53-60).  [PMID:2886124]
3. T L Perry,K Jones,S Hansen,R A Wall.  (1987-03-20)  4-phenylpyridine and three other analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lack dopaminergic nigrostriatal neurotoxicity in mice and marmosets..  Neuroscience letters,  75  ((1)): (65-70).  [PMID:3106859]
4. K S Hsu,S Y Lin-Shiau.  (1993-09-01)  Potentiation of MPTP by 4-phenylpyridine on the neuromuscular blockade in mouse phrenic nerve-diaphragm..  Neuropharmacology,  32  ((9)): (877-883).  [PMID:7901791]
5. M R Gluck,M J Krueger,R R Ramsay,S O Sablin,T P Singer,W J Nicklas.  (1994-02-04)  Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations..  The Journal of biological chemistry,  269  ((5)): (3167-3174).  [PMID:8106350]
6. P Sett,S Chattopadhyay,P K Mallick.  (2000-05-16)  Raman excitation profiles and excited state molecular configurations of three isomeric phenyl pyridines..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  56  ((5)): (855-875).  [PMID:10809061]
7. Wendy M Barendt,Stephen H Wright.  (2002-04-16)  The human organic cation transporter (hOCT2) recognizes the degree of substrate ionization..  The Journal of biological chemistry,  277  ((25)): (22491-22496).  [PMID:11953440]
8. Giulia Caron,Giuseppe Ermondi.  (2005-04-29)  Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk)..  Journal of medicinal chemistry,  48  ((9)): (3269-3279).  [PMID:15857133]
9. Camilla C Golfeto,Gustavo Von Poelhsitz,Heloísa S Selistre-de-Araújo,Márcio P de Araujo,Javier Ellena,Eduardo E Castellano,Luiz G L Lopes,Icaro S Moreira,Alzir A Batista.  (2010-02-02)  Synthesis, characterization and cytotoxic activities of the [RuCl2(NO)(dppp)(L)]PF6 complexes..  Journal of inorganic biochemistry,  104  ((5)): (489-495).  [PMID:20117840]
10. Cemal Parlak,Ozgür Alver,Mustafa Senyel.  (2011-03-08)  Vibrational spectroscopic study on some Hofmann-Td type clathrates: Ni(4-phenylpyridine)2M(CN)4·2G (M=Cd or Hg, G=1,4-dioxane)..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  78  ((5)): (1487-1491).  [PMID:21377405]
11. Germano Giuliani,Andrea Cappelli,Mario Matarrese,Valeria Masiello,Elia Anna Turolla,Cristina Monterisi,Ferruccio Fazio,Maurizio Anzini,Galla Pericot Mohr,Daniela Riitano,Federica Finetti,Lucia Morbidelli,Marina Ziche,Gianluca Giorgi,Salvatore Vomero.  (2011-03-23)  Non-peptide NK1 receptor ligands based on the 4-phenylpyridine moiety..  Bioorganic & medicinal chemistry,  19  ((7)): (2242-2251).  [PMID:21421318]
12. Stéphanie Romand,Julie Schappler,Jean-Luc Veuthey,Pierre-Alain Carrupt,Sophie Martel.  (2014-07-06)  cIEF for rapid pKa determination of small molecules: a proof of concept..  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences,  63  (14-21).  [PMID:24995703]
13. Daniel Ejarque,Teresa Calvet,Mercè Font-Bardia,Josefina Pons.  (2020-08-14)  Construction of Zn(II) Linear Trinuclear Secondary Building Units from A Coordination Polymer Based on α-Acetamidocinnamic Acid and 4-Phenylpyridine..  Molecules (Basel, Switzerland),  25  ((16)):   [PMID:32784822]
14. A D Vaz,M J Coon,H Peegel,K M Menon.  (1992-01-01)  Substituted pyridines: nonsteroidal inhibitors of human placental aromatase cytochrome P-450..  Drug metabolism and disposition: the biological fate of chemicals,  20  ((1)): (108-112).  [PMID:1346984]
15. L A Carr,J K Basham,B K York,P P Rowell.  (1992-05-14)  Inhibition of uptake of 1-methyl-4-phenylpyridinium ion and dopamine in striatal synaptosomes by tobacco smoke components..  European journal of pharmacology,  215  ((2-3)): (285-287).  [PMID:1396992]
16. L A Carr,J K Basham.  (1991-01-01)  Effects of tobacco smoke constituents on MPTP-induced toxicity and monoamine oxidase activity in the mouse brain..  Life sciences,  48  ((12)): (1173-1177).  [PMID:2002748]
17. I Irwin,J W Langston,L E DeLanney.  (1987-02-23)  4-Phenylpyridine (4PP) and MPTP: the relationship between striatal MPP+ concentrations and neurotoxicity..  Life sciences,  40  ((8)): (731-740).  [PMID:3492652]
18. K S Hsu,C C Huang,M T Su,J J Tsai.  (1996-11-01)  L-deprenyl (selegiline) decreases excitatory synaptic transmission in the rat hippocampus via a dopaminergic mechanism..  The Journal of pharmacology and experimental therapeutics,  279  ((2)): (740-747).  [PMID:8930179]
19. C C Huang,J J Tsai,K S Hsu.  (1997-04-04)  L-deprenyl (selegiline) limits the repetitive firing of action potentials in rat hippocampal CA1 neurons via a dopaminergic mechanism..  Brain research,  753  ((1)): (27-35).  [PMID:9125428]
20. Monica Brivio,R Edwin Oosterbroek,Willem Verboom,Albert van den Berg,David N Reinhoudt.  (2005-09-22)  Simple chip-based interfaces for on-line monitoring of supramolecular interactions by nano-ESI MS..  Lab on a chip,  ((10)): (1111-1122).  [PMID:16175268]
21. Dengmeng Song,Bo Li,Xin Li,Xuzhuo Sun,Jun Li,Chengbo Li,Tongyu Xu,Yong Zhu,Fei Li,Ning Wang.  (2019-11-05)  Orthogonal Supramolecular Assembly Triggered by Inclusion and Exclusion Interactions with Cucurbit[7]uril for Photocatalytic H2 Evolution..  ChemSusChem,  13  ((2)): (394-399).  [PMID:31682086]
22. Chao Liu, Lei Shi, Jiaxu Zhang, Jianmin Sun.  (2022)  One-pot synthesis of pyridine-based ionic hyper-cross-linked polymers with hierarchical pores for efficient CO2 capture and catalytic conversion.  CHEMICAL ENGINEERING JOURNAL,  427  (131633).  [PMID:] [10.1016/j.cej.2021.131633]
23. Xin Xiao, Shunheng Tu, Chunxia Zheng, Huan Zhong, Xiaoxi Zuo, Junmin Nan.  (2015)  L-Asparagine-assisted synthesis of flower-like β-Bi2O3 and its photocatalytic performance for the degradation of 4-phenylphenol under visible-light irradiation.  RSC Advances,  (91): (74977-74985).  [PMID:] [10.1039/C5RA13985F]

Solution Calculators