Basic Description

Synonyms	144789-75-3 \| 4-(Trifluoromethyl)-L-phenylglycine \| 4-(Trifluoromethyl)phenylglycine \| (2S)-2-amino-2-[4-(trifluoromethyl)phenyl]acetic acid \| (S)-2-AMINO-2-(4-(TRIFLUOROMETHYL)PHENYL)ACETIC ACID \| Benzeneacetic acid, a-amino-4-(trifluoromethyl)-, (aS)- \| (2S)-2-ammo
Specifications & Purity	≥98%

Associated Targets(non-human)

Slc1a5 Amino acid transporter (271 Activities)

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

IUPAC Name	(2S)-2-amino-2-[4-(trifluoromethyl)phenyl]acetic acid
INCHI	InChI=1S/C9H8F3NO2/c10-9(11,12)6-3-1-5(2-4-6)7(13)8(14)15/h1-4,7H,13H2,(H,14,15)/t7-/m0/s1
InChi Key	FANMQHUKZBBELZ-ZETCQYMHSA-N
Canonical SMILES	C1=CC(=CC=C1C(C(=O)O)N)C(F)(F)F
Isomeric SMILES	C1=CC(=CC=C1[C@@H](C(=O)O)N)C(F)(F)F
WGK Germany	3
PubChem CID	1476637
Molecular Weight	219.16

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Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RIDADR	NONHforallmodesoftransport

1. Zhang J et al.. (2021) Severe deficiency of the voltage-gated sodium channel NaV1.2 elevates neuronal excitability in adult mice.. Cell Rep, 36 (5): (109495). [PMID:34348148]

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