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4OH-GTS-21 , CAS No.O607194, Agonist of nicotinic acetylcholine receptor α7 subunit

  • Moligand™
Item Number
O607194
Grouped product items
SKUSizeAvailabilityPrice Qty
O607194-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,190.90
O607194-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,334.90
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nicotinic acetylcholine receptor α7 subunit Agonist

Basic Description

Synonyms4-OH-GTS-21;4-OH-MBA
Specifications & PurityMoligand™
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of nicotinic acetylcholine receptor α7 subunit

Associated Targets

CHRND Tclin Acetylcholine receptor subunit delta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRNA7 Tchem Neuronal acetylcholine receptor subunit alpha-7 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRNA3 Tclin Neuronal acetylcholine receptor subunit alpha-3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRNB2 Tclin Neuronal acetylcholine receptor subunit beta-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 3-methoxy-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]phenol
INCHI InChI=1S/C18H18N2O2/c1-22-17-11-16(21)7-6-13(17)10-14-4-3-9-20-18(14)15-5-2-8-19-12-15/h2,5-8,10-12,21H,3-4,9H2,1H3/b14-10+
InChi Key KXAAIPFSUGPVMQ-GXDHUFHOSA-N
Canonical SMILES COc1cc(O)ccc1/C=C/1\CCCN=C1c1cccnc1
Isomeric SMILES COC1=C(C=CC(=C1)O)/C=C/2\CCCN=C2C3=CN=CC=C3
PubChem CID 135508231

Certificates

Certificate of Analysis(COA)

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Related Documents

 SDS

 Specification Sheet

References

1. Kombo DC, Mazurov A, Tallapragada K, Hammond PS, Chewning J, Hauser TA, Vasquez-Valdivieso M, Yohannes D, Talley TT, Taylor P et al..  (2011)  Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands..  Eur J Med Chem,  46  (11): (5625-35).  [PMID:21986237]

Solution Calculators

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