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(4R-cis)-5-methyl-2-oxoimidazolidine-4-hexanoic acid - 95%, high purity , CAS No.533-48-2

  • ≥95%
Item Number
R303913
Grouped product items
SKUSizeAvailabilityPrice Qty
R303913-250mg
250mg
In stock
$109.90
R303913-1g
1g
In stock
$299.90
R303913-5g
5g
In stock
$1,199.90

Basic Description

Synonymsd-Desthiobiotin|dethiobiotin|533-48-2|d-Dethiobiotin|Desthiobiotin|(+)-Dethiobiotin|Biotin, dethio-|6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid|(4R,5S)-dethiobiotin|Desthiobiotin, DL-|(+/-)-Desthiobiotin|Desthiobiotin, (+/-)-|dl-Dethiobiotin|
Specifications & Purity≥95%
Biochemical and Physiological MechanismsDesthiobiotin is a non-sulfur containing biotin derivative that binds less strongly to biotin-binding proteins and is easily dislocated by biotin.
Storage TempStore at 2-8°C
Shipped InWet ice
Product Description

D-desthiobiotin has been used in affinity chromatography and protein chromatography.D-desthiobiotin can be used for protein labeling, detection, and separation.

Product Application:
d-Desthiobiotin has been used as a component of elution buffers:
to elute the precipitated proteins from the resin during coimmunoprecipitation
to elute human Cdc45–MCM–GINS (CMG) helicase during chromatographic protein purification
to elute the heterodimeric kinesin family member 3A/B (KIF3A/B) and kinesin associated protein 3 (KAP3)-binding APC armadillo (APCARM) domain during chromatographic purification
d-Desthiobiotin is used in affinity chromatography and protein chromatography. d-Desthiobiotin can be used for protein labeling, detection and isolation.

Associated Targets

CBX1 Tbio Chromobox protein homolog 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GMNN Tbio Geminin 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

POLH Tchem DNA polymerase eta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDE Tchem Insulin-degrading enzyme 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

WRN Tbio Werner syndrome ATP-dependent helicase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

BLM Tchem Bloom syndrome protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ABL1 Tclin Tyrosine-protein kinase ABL1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

PPARG Tclin Peroxisome proliferator-activated receptor gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4A Tchem Lysine-specific demethylase 4A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR2E3 Tchem Photoreceptor-specific nuclear receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 6-[(4R,5S)-5-methyl-2-oxoimidazolidin-4-yl]hexanoic acid
INCHI InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1
InChi Key AUTOLBMXDDTRRT-JGVFFNPUSA-N
Canonical SMILES CC1C(NC(=O)N1)CCCCCC(=O)O
Isomeric SMILES C[C@H]1[C@H](NC(=O)N1)CCCCCC(=O)O
PubChem CID 445027
Molecular Weight 214.26

Certificates

Certificate of Analysis(COA)

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18 results found

Lot NumberCertificate TypeDateItem
D2411346Certificate of AnalysisMar 28, 2024 R303913
D2411348Certificate of AnalysisMar 28, 2024 R303913
I2305680Certificate of AnalysisAug 11, 2023 R303913
I2305679Certificate of AnalysisAug 11, 2023 R303913
I2305653Certificate of AnalysisAug 11, 2023 R303913
I2305654Certificate of AnalysisAug 11, 2023 R303913
I2305678Certificate of AnalysisAug 11, 2023 R303913
L2203367Certificate of AnalysisNov 16, 2022 R303913
L2203363Certificate of AnalysisNov 16, 2022 R303913
L2203353Certificate of AnalysisNov 16, 2022 R303913
H2304172Certificate of AnalysisNov 16, 2022 R303913
J2221522Certificate of AnalysisJul 23, 2022 R303913
J2221525Certificate of AnalysisJul 23, 2022 R303913
J2221528Certificate of AnalysisJul 23, 2022 R303913
F2210093Certificate of AnalysisMay 12, 2022 R303913
F2210092Certificate of AnalysisMay 12, 2022 R303913
A2215588Certificate of AnalysisDec 20, 2021 R303913
A2215587Certificate of AnalysisDec 20, 2021 R303913

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Chemical and Physical Properties

Flash Point(°C)241.9 °C
Boil Point(°C)476.4 °C at 760 mmHg
Melt Point(°C)156-158 °C

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