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5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) - Dye content 90%, high purity , CAS No.36951-72-1

  • Dye content 90%
Item Number
T478379
Grouped product items
SKUSizeAvailabilityPrice Qty
T478379-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$208.90
T478379-250mg
250mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$458.90

Basic Description

Specifications & PurityDye content 90%
Product Description

5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(ptoluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent ¹O2luminescence signals on incubation with the fungus,Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) (TMPyP), a cationic porphyrin, was used to study the noncovalent functionalization of graphene with cationic porphyrins using UV–vis and fluorescence methods. TMPyP may be used as an optical indicator ligand in the preparation of multifunctional membrane for visual warning and enhanced adsorptive removal of cadmium ions in aqueous solutions. TMPyP was also used to fabricate the (TMPyP)- single-walled carbon nanotubes (SWNT)/sodium copper chlorophyllin-SWNT layer-by-layer film from noncovalently adsorbed composites.

Names and Identifiers

Molecular Weight 1363.6
Reaxy-Rn 5237096

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Solubility water: soluble 50mM(lit.)

Safety and Hazards(GHS)

Reaxy-Rn 5237096

Related Documents

References

1. De Gao,Rodney R Agayan,Hao Xu,Martin A Philbert,Raoul Kopelman.  (2006-11-09)  Nanoparticles for two-photon photodynamic therapy in living cells..  Nano letters,  ((11)): (2383-2386).  [PMID:17090062]
2. Wanhua Lei,Guoyu Jiang,Qianxiong Zhou,Baowen Zhang,Xuesong Wang.  (2010-09-09)  Greatly enhanced binding of a cationic porphyrin towards bovine serum albumin by cucurbit[8]uril..  Physical chemistry chemical physics : PCCP,  12  ((40)): (13255-13260).  [PMID:20824256]
3. Aleksandra Wojcik,Prashant V Kamat.  (2010-10-30)  Reduced graphene oxide and porphyrin. An interactive affair in 2-D..  ACS nano,  ((11)): (6697-6706).  [PMID:21028793]
4. Anabela Tavares,Sandra R S Dias,Carla M B Carvalho,Maria A F Faustino,João P C Tomé,Maria G P M S Neves,Augusto C Tomé,José A S Cavaleiro,Ângela Cunha,Newton C M Gomes,Eliana Alves,Adelaide Almeida.  (2011-07-30)  Mechanisms of photodynamic inactivation of a gram-negative recombinant bioluminescent bacterium by cationic porphyrins..  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,  10  ((10)): (1659-1669).  [PMID:21799996]
5. Xiaojie Cui,Gu Yuan.  (2011-09-15)  Formation and recognition of G-quadruplex in promoter of c-myb oncogene by electrospray ionization mass spectrometry..  Journal of mass spectrometry : JMS,  46  ((9)): (849-855).  [PMID:21915947]
6. Yongxiang Wang,Limin Xiong,Fenghua Geng,Fuqiang Zhang,Maotian Xu.  (2011-10-04)  Design of a dual-signaling sensing system for fluorescent ratiometric detection of Al3+ ion based on the inner-filter effect..  The Analyst,  136  ((22)): (4809-4814).  [PMID:21966670]
7. Corona M Cassidy,Ryan F Donnelly,J Stuart Elborn,Nicholas D Magee,Michael M Tunney.  (2011-11-15)  Photodynamic Antimicrobial Chemotherapy (PACT) in combination with antibiotics for treatment of Burkholderia cepacia complex infection..  Journal of photochemistry and photobiology. B, Biology,  106  (95-100).  [PMID:22079165]
8. Ting-xiu Ye,Shu-lan Ye,Dong-mei Chen,Qing-ai Chen,Bin Qiu,Xi Chen.  (2011-11-29)  Spectroscopic characterization of tetracationic porphyrins and their noncovalent functionalization with graphene..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  86  (467-471).  [PMID:22119123]
9. Johannes Regensburger,Alena Knak,Tim Maisch,Michael Landthaler,Wolfgang Bäumler.  (2012-01-11)  Fatty acids and vitamins generate singlet oxygen under UVB irradiation..  Experimental dermatology,  21  ((2)): (135-139).  [PMID:22229443]
10. Shinobu Sato,Shigeori Takenaka.  (2012-01-17)  PCR-free telomerase assay using chronocoulometry coupled with hexaammineruthenium(III) chloride..  Analytical chemistry,  84  ((3)): (1772-1775).  [PMID:22242860]
11. Mark J Morris,Katherine L Wingate,Jagannath Silwal,Thomas C Leeper,Soumitra Basu.  (2012-01-24)  The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells..  Nucleic acids research,  40  ((9)): (4137-4145).  [PMID:22266651]
12. Tim Maisch,Franz Spannberger,Johannes Regensburger,Ariane Felgenträger,Wolfgang Bäumler.  (2012-02-23)  Fast and effective: intense pulse light photodynamic inactivation of bacteria..  Journal of industrial microbiology & biotechnology,  39  ((7)): (1013-1021).  [PMID:22354734]
13. I Banerjee,K K Mehta,J S Dordick,R S Kane.  (2012-08-29)  Light-activated porphyrin-based formulations to inactivate bacterial spores..  Journal of applied microbiology,  113  ((6)): (1461-1467).  [PMID:22925067]
14. Huy T Le,M Clarke Miller,Robert Buscaglia,William L Dean,Patrick A Holt,Jonathan B Chaires,John O Trent.  (2012-10-31)  Not all G-quadruplexes are created equally: an investigation of the structural polymorphism of the c-Myc G-quadruplex-forming sequence and its interaction with the porphyrin TMPyP4..  Organic & biomolecular chemistry,  10  ((47)): (9393-9404).  [PMID:23108607]
15. Sara Chiarella,Antonella De Cola,Giovanni Luca Scaglione,Erminia Carletti,Vincenzo Graziano,Daniela Barcaroli,Carlo Lo Sterzo,Adele Di Matteo,Carmine Di Ilio,Brunangelo Falini,Alessandro Arcovito,Vincenzo De Laurenzi,Luca Federici.  (2013-01-19)  Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA..  Nucleic acids research,  41  ((5)): (3228-3239).  [PMID:23328624]
16. Qingqing He,Ping Zeng,Jia-Heng Tan,Tian-Miao Ou,Lian-Quan Gu,Zhi-Shu Huang,Ding Li.  (2014-03-19)  G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression..  Biochimica et biophysica acta,  1840  ((7)): (2222-2233).  [PMID:24631651]
17. Yuangang Li,Weina Wang,Wan Ru Leow,Bowen Zhu,Fanben Meng,Liyan Zheng,Jia Zhu,Xiaodong Chen.  (2014-03-26)  Optoelectronics of organic nanofibers formed by co-assembly of porphyrin and perylenediimide..  Small (Weinheim an der Bergstrasse, Germany),  10  ((14)): (2776-2781).  [PMID:24664501]
18. B H Laster,C Isaacson,E Perets,M Msamra,E Priel,J Kalef-Ezra,J Kost.  (2014-07-31)  Keeping those telomeres short! an innovative intratumoral long-term drug delivery system..  Journal of cancer research and clinical oncology,  141  ((1)): (23-34).  [PMID:25073436]
19. Rui-Xiang Wang,Jing-Jing Fan,You-Jun Fan,Jing-Ping Zhong,Li Wang,Shi-Gang Sun,Xing-Can Shen.  (2014-11-05)  Platinum nanoparticles on porphyrin functionalized graphene nanosheets as a superior catalyst for methanol electrooxidation..  Nanoscale,  ((24)): (14999-15007).  [PMID:25363456]
20. Marek Scholz,Anna-Louisa Biehl,Roman Dědic,Jan Hála.  (2015-01-17)  The singlet-oxygen-sensitized delayed fluorescence in mammalian cells: a time-resolved microscopy approach..  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,  14  ((4)): (700-713).  [PMID:25591544]
21. Sana S Dastgheyb,Cyrus B Toorkey,Irving M Shapiro,Noreen J Hickok.  (2015-04-22)  Porphyrin-adsorbed Allograft Bone: A Photoactive, Antibiofilm Surface..  Clinical orthopaedics and related research,  473  ((9)): (2865-2873).  [PMID:25894811]
22. Kai Liu,Han Zhang,Ruirui Xing,Qianli Zou,Xuehai Yan.  (2017-12-02)  Biomimetic Oxygen-Evolving Photobacteria Based on Amino Acid and Porphyrin Hierarchical Self-Organization..  ACS nano,  11  ((12)): (12840-12848).  [PMID:29195044]
23. Alexander Müller,Annegret Preuß,Tobias Bornhütter,Isabell Thomas,Andrea Prager,Agnes Schulze,Beate Röder.  (2018-08-25)  Electron beam functionalized photodynamic polyethersulfone membranes - photophysical characterization and antimicrobial activity..  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,  17  ((10)): (1346-1354).  [PMID:30141813]
24. Isabel O L Bacellar,Rodrigo M Cordeiro,Pascal Mahling,Mauricio S Baptista,Beate Röder,Steffen Hackbarth.  (2019-02-05)  Oxygen distribution in the fluid/gel phases of lipid membranes..  Biochimica et biophysica acta. Biomembranes,  1861  ((4)): (879-886).  [PMID:30716292]
25. Catarina I V Ramos,Susana P Almeida,Leandro M O Lourenço,Patrícia M R Pereira,Rosa Fernandes,M Amparo F Faustino,João P C Tomé,Josué Carvalho,Carla Cruz,M Graça P M S Neves.  (2019-02-20)  Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures..  Molecules (Basel, Switzerland),  24  ((4)):   [PMID:30781675]
26. Sawsan Almohammed,Sebastian Tade Barwich,Andrew K Mitchell,Brian J Rodriguez,James H Rice.  (2019-06-09)  Enhanced photocatalysis and biomolecular sensing with field-activated nanotube-nanoparticle templates..  Nature communications,  10  ((1)): (2496-2496).  [PMID:31175281]
27. Xiangyu Sun,Bing Liu,Xianli Chen,Huichao Lin,Yanbo Peng,Yanyu Li,Haoran Zheng,Yibin Xu,Xulin Ou,Siqi Yan,Zonghai Wu,Shujun Deng,Luyong Zhang,Ping Zhao.  (2019-06-21)  Aptamer-assisted superparamagnetic iron oxide nanoparticles as multifunctional drug delivery platform for chemo-photodynamic combination therapy..  Journal of materials science. Materials in medicine,  30  ((7)): (76-76).  [PMID:31218573]
28. Eckl, et al..  (2021)  First Report on Photodynamic Inactivation of Archaea Including a Novel Method for High-Throughput Reduction Measurement..  Photochemistry and Photobiology,  96  (883-889).  [PMID:32073658]
29. Monika Kossakowska-Zwierucho,Grzegorz Szewczyk,Tadeusz Sarna,Joanna Nakonieczna.  (2020-04-01)  Farnesol potentiates photodynamic inactivation of Staphylococcus aureus with the use of red light-activated porphyrin TMPyP..  Journal of photochemistry and photobiology. B, Biology,  206  (111863-111863).  [PMID:32224392]
30. Hengye Chen,Qiong Shi,Haiyan Fu,Ou Hu,Yao Fan,Lu Xu,Lei Zhang,Wei Lan,Donglei Sun,Tianming Yang,Yuanbin She.  (2020-05-14)  Rapid detection of five pesticide residues using complexes of gold nanoparticle and porphyrin combined with ultraviolet visible spectrum..  Journal of the science of food and agriculture,  100  ((12)): (4464-4473).  [PMID:32399965]
31. Fatma Demir Duman,Matej Sebek,Nguyen T K Thanh,Marilena Loizidou,Kaveh Shakib,Alexander J MacRobert.  (2020-05-19)  Enhanced photodynamic therapy and fluorescence imaging using gold nanorods for porphyrin delivery in a novel in vitro squamous cell carcinoma 3D model..  Journal of materials chemistry. B,  ((23)): (5131-5142).  [PMID:32420578]
32. Alexandra Vaccaro,Yosef Kaplan Dor,Keishi Nambara,Elizabeth A Pollina,Cindy Lin,Michael E Greenberg,Dragana Rogulja.  (2020-06-06)  Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut..  Cell,  181  ((6)): (1307-1328).  [PMID:32502393]
33. Kihun Jang,Il Woong Baek,Sung Yul Back,Heejoon Ahn.  (2011-11-30)  Electrospinning of porphyrin/polyvinyl alcohol (PVA) nanofibers and their acid vapor sensing capability..  Journal of nanoscience and nanotechnology,  11  ((7)): (6102-6108).  [PMID:22121666]
34. Luciane M Almeida,Fabiana F Zanoelo,Kelly P Castro,Iouri E Borissevitch,Célia M A Soares,Pablo J Gonçalves.  (2012-02-16)  Cell survival and altered gene expression following photodynamic inactivation of Paracoccidioides brasiliensis..  Photochemistry and photobiology,  88  ((4)): (992-1000).  [PMID:22332981]
35. Elysia P M T Cohn,Kun-Liang Wu,Thomas R R Pettus,Norbert O Reich.  (2012-03-15)  A new strategy for detection and development of tractable telomerase inhibitors..  Journal of medicinal chemistry,  55  ((8)): (3678-3686).  [PMID:22413845]
36. Vladimir L Malinovskii,Alina L Nussbaumer,Robert Häner.  (2012-04-12)  Oligopyrenotides: chiral nanoscale templates for chromophore assembly..  Angewandte Chemie (International ed. in English),  51  ((20)): (4905-4908).  [PMID:22492542]
37. Marina K Kuimova.  (2012-07-19)  Mapping viscosity in cells using molecular rotors..  Physical chemistry chemical physics : PCCP,  14  ((37)): (12671-12686).  [PMID:22806312]
38. Anja Eichner,Fernanda Pereira Gonzales,Ariane Felgenträger,Johannes Regensburger,Thomas Holzmann,Wulf Schneider-Brachert,Wolfgang Bäumler,Tim Maisch.  (2012-08-03)  Dirty hands: photodynamic killing of human pathogens like EHEC, MRSA and Candida within seconds..  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology,  12  ((1)): (135-147).  [PMID:22855122]
39. Sherif A El-Safty,Mohamed A Shenashen,Mohamed Khairy.  (2012-09-04)  Optical detection/collection of toxic Cd(II) ions using cubic Ia3d aluminosilica mesocage sensors..  Talanta,  98  (69-78).  [PMID:22939130]
40. Ryan Dosselli,Renato Millioni,Lucia Puricelli,Paolo Tessari,Giorgio Arrigoni,Cinzia Franchin,Anna Segalla,Enrico Teardo,Elena Reddi.  (2012-09-25)  Molecular targets of antimicrobial photodynamic therapy identified by a proteomic approach..  Journal of proteomics,  77  (329-343).  [PMID:23000218]
41. Sintayehu Manaye,Ramon Eritja,Anna Aviñó,Joaquim Jaumot,Raimundo Gargallo.  (2012-09-25)  Porphyrin binding mechanism is altered by protonation at the loops in G-quadruplex DNA formed near the transcriptional activation site of the human c-kit gene..  Biochimica et biophysica acta,  1820  ((12)): (1987-1996).  [PMID:23000573]
42. Takuma Arai,Manabu Tanaka,Hiroyoshi Kawakami.  (2012-10-02)  Porphyrin-containing electrospun nanofibers: positional control of porphyrin molecules in nanofibers and their catalytic application..  ACS applied materials & interfaces,  ((10)): (5453-5457).  [PMID:23020508]
43. Zhong De Liu,Heng Xin Zhao,Cheng Zhi Huang.  (2012-12-20)  Obstruction of photoinduced electron transfer from excited porphyrin to graphene oxide: a fluorescence turn-on sensing platform for iron (III) ions..  PloS one,  ((12)): (e50367-e50367).  [PMID:23251366]
44. Sharif M Abdelghany,Daniela Schmid,Jill Deacon,Jakub Jaworski,Francois Fay,Kirsty M McLaughlin,Julie A Gormley,James F Burrows,Daniel B Longley,Ryan F Donnelly,Christopher J Scott.  (2013-01-19)  Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles..  Biomacromolecules,  14  ((2)): (302-310).  [PMID:23327610]
45. Xin-Ying Zhuang,Yong-Gang Yao.  (2013-04-23)  Mitochondrial dysfunction and nuclear-mitochondrial shuttling of TERT are involved in cell proliferation arrest induced by G-quadruplex ligands..  FEBS letters,  587  ((11)): (1656-1662).  [PMID:23603390]
46. Tomoyuki Watanabe,Masao Saotome,Mamoru Nobuhara,Atsushi Sakamoto,Tsuyoshi Urushida,Hideki Katoh,Hiroshi Satoh,Makoto Funaki,Hideharu Hayashi.  (2014-03-19)  Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance..  Experimental cell research,  323  ((2)): (314-325).  [PMID:24631294]
47. Thibaut Imberdis,James T Heeres,Han Yueh,Cheng Fang,Jessie Zhen,Celeste B Rich,Marcie Glicksman,Aaron B Beeler,David A Harris.  (2016-11-03)  Identification of Anti-prion Compounds using a Novel Cellular Assay..  The Journal of biological chemistry,  291  ((50)): (26164-26176).  [PMID:27803163]
48. Pavel Kubát,Petr Henke,Jiří Mosinger.  (2019-01-18)  The effect of iodide and temperature on enhancing antibacterial properties of nanoparticles with an encapsulated photosensitizer..  Colloids and surfaces. B, Biointerfaces,  176  (334-340).  [PMID:30654240]
49. Sepideh NouhzadehMalekshah,Reza Fekrazad,Majid Bargrizan,Katayoun Am Kalhori.  (2019-03-28)  Evaluation of laser fluorescence in combination with photosensitizers for detection of demineralized lesions..  Photodiagnosis and photodynamic therapy,  26  (300-305).  [PMID:30914391]
50. Ha Young Cho,Young-Ae Lee,Ye Sol Oh,Gil Jun Lee,Yoon Jung Jang,Seog K Kim.  (2019-07-17)  Binding mode of a cationic porphyrin to parallel and antiparallel thrombin binding aptamer G-quadruplex..  Journal of biomolecular structure & dynamics,  38  ((9)): (2686-2692).  [PMID:31307279]
51. Liwei Sun,Lingjie Song,Xu Zhang,Rongtao Zhou,Jinghua Yin,Shifang Luan.  (2020-06-04)  Poly(γ-glutamic acid)-based electrospun nanofibrous mats with photodynamic therapy for effectively combating wound infection..  Materials science & engineering. C, Materials for biological applications,  113  (110936-110936).  [PMID:32487377]
52. Natalya E Sannikova,Ivan O Timofeev,Alexey S Chubarov,Natalya Sh Lebedeva,Aleksandr S Semeikin,Igor A Kirilyuk,Yuri P Tsentalovich,Matvey V Fedin,Elena G Bagryanskaya,Olesya A Krumkacheva.  (2020-09-16)  Application of EPR to porphyrin-protein agents for photodynamic therapy..  Journal of photochemistry and photobiology. B, Biology,  211  (112008-112008).  [PMID:32932136]
53. Tao Wang,Sergiy Korposh,Stephen James,Seung-Woo Lee.  (2020-11-18)  Long-period grating fiber-optic sensors exploiting molecularly imprinted TiO2 nanothin films with photocatalytic self-cleaning ability..  Mikrochimica acta,  187  ((12)): (663-663).  [PMID:33201381]

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