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5(6)-Carboxyfluorescein, mixture of isomers - ≥95% (HPLC), high purity , CAS No.72088-94-9
Amine-reactive pH-senstive fluorescent label. Covalently labels proteins and peptides.
Basic Description Synonyms 5(6)-carboxyfluorescein|72088-94-9|5(6)-FAM|1171493-85-8|MFCD00151081|3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid;3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid|3',6'-Dihydroxy-3-oxo-3H-spiro[isobenzo Specifications & Purity ≥95% (HPLC) Storage Temp Protected from light,Store at -20°C,Desiccated Shipped In Ice chest + Ice pads Product Description Fluorescent probe material, have a strong green fluorescence under an alkaline condition, widely used in the fluorescence analysis, the tracer dye, pH indicator and synthetic derivatives of the carboxyl fluorescein. Intracellular pH probe.Its derivatives such as 2′,7′-bis (2-carboxyethyl)-5(6)-carboxyfluorescein are used to measure changes in intracellular pH (pHi) and processes such as dendrimer aggregation and absorption.
Names and Identifiers IUPAC Name 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid;3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-5-carboxylic acid INCHI InChI=1S/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25) InChi Key BPVHBBXCESDRKW-UHFFFAOYSA-N Canonical SMILES C1=CC2=C(C=C1C(=O)O)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O.C1=CC2=C(C=C1C(=O)O)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O Isomeric SMILES C1=CC2=C(C=C1C(=O)O)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O.C1=CC2=C(C=C1C(=O)O)C(=O)OC23C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O WGK Germany 3 Alternate CAS 1171493-85-8 PubChem CID 44119975 Molecular Weight 376.32
Chemical and Physical Properties Sensitivity Light & Moisture Sensitive Melt Point(°C) 275°C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H319: Causes serious eye irritation
H317: May cause an allergic skin reaction
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P264+P265: Wash hands [and …] thoroughly after handling. Do not touch eyes.
P337+P317: If eye irritation persists: Get medical help.
WGK Germany 3
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