5-Aminosalicylic Acid, the metabolite of sulphasalazine, has been shown to inhibit PGDH (prostaglandin 15-hydroxydehydrogenase) in human placenta and bovine lung. Further studies show that this antiinflammatory compound also inhibits leukotriene formation
Storage Temp
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of Peroxisome proliferator-activated receptor-γ
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Mesalamine is an anti-inflammatory compound. 5-Aminosalicylic acid is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is brown in color and can be read spectrophotometrically at 450 nm. The reaction may be stopped with 3 N NaOH and read
Soluble in 1 M hydrochloric acid (50 mg/ml), water (0.84 g/l at 20 °C), alcohol, DMSO (~4 mg/ml), DMF (~1.6 mg/ml), PBS(pH=7.2) (~1.7 mg/ml), methanol, water (1.7 mg/ml at 25 °C), and ethanol (31 mg/ml at 25 °C). Insoluble in diethyl ether, and n-octan
F2405021