5'-AMP-Na2 - 99%, high purity , CAS No.4578-31-8

  • ≥99%
Item Number
A100357
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A100357-1g
1g
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$9.90
A100357-5g
5g
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$25.90
A100357-25g
25g
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Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$75.90
A100357-100g
100g
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$270.90
A100357-500g
500g
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$1,218.90

AMPK activator.

View related series
Adenosine Receptor GPCR/G Protein

Basic Description

SynonymsAdenosine 5'-monophosphate disodium salt | UNII-T1WZ11DSRN | 5'-ADENYLIC ACID, SODIUM SALT (1:2) | AMP disodium salt | MFCD08689634 | Adenosine 5'-monophosphate, disodium salt | Adenosine 5'-monophosphoric acid disodium salt | A884311 | Disodium adenosine
Specifications & Purity≥99%
Biochemical and Physiological MechanismsNucleotide involved in the reactions of cellular energy transfers. Acts as an activator of AMP-activated protein kinase (AMPK). Used as a substrate for enzymes such as AMP-thymidine kinase, AMP deaminase and 5'-nucleotidase.
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Adenosine 5′-Monophosphate, Disodium Salt is a nucleotide that is widely distributed in nature. Adenosine 5′-Monophosphate, Disodium Salt is an activator of AMPK.
A nucleotide involved in the reactions of cellular energy transfers.

Names and Identifiers

IUPAC Name disodium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
INCHI InChI=1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
InChi Key QGXLVXZRPRRCRP-IDIVVRGQSA-L
Canonical SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])[O-])O)O)N.[Na+].[Na+]
Alternate CAS 13474-03-8
PubChem CID 20712
Molecular Weight 391.18

Certificates

Certificate of Analysis(COA)

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9 results found

Lot NumberCertificate TypeDateItem
D2409100Certificate of AnalysisMar 14, 2024 A100357
D2409101Certificate of AnalysisMar 14, 2024 A100357
F1918201Certificate of AnalysisApr 11, 2023 A100357
G2222051Certificate of AnalysisJun 11, 2022 A100357
G2222054Certificate of AnalysisJun 11, 2022 A100357
G2222055Certificate of AnalysisJun 11, 2022 A100357
G2222178Certificate of AnalysisJun 11, 2022 A100357
J2431236Certificate of AnalysisJun 11, 2022 A100357
B2418220Certificate of AnalysisDec 07, 2021 A100357

Chemical and Physical Properties

SolubilitySoluble in water (50 mg/ml), DMSO, and methanol.
SensitivityAir and moisture sensitive
Specific Rotation[α][α]20/D ?43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
Melt Point(°C)300 °C

Related Documents

Citations of This Product

1. Liu Yujie, Gao Ran, Liu Xingcen, Zheng Jinhua, Wu Xia.  (2023)  High-efficiency fluorescent coordination polymer nanoparticles co-doped with Ce3+/Tb3+ ions for curcumin detection.  MICROCHIMICA ACTA,  190  (9): (1-11).  [PMID:37587349] [10.1007/s00604-023-05933-6]
2. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan.  (2023)  Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (69).  [PMID:] [10.1016/j.cjche.2023.01.009]
3. Chujing Yang, Zhiwei Zhang, Jingqi Chen, Xinying Zhang, Yankai Dai, Xuyi Li, Yingying Chen, Jiaqiang Xu, Lingyan Feng.  (2023)  Multiple switchable circularly polarized luminescence from nucleotide/terbium(III) complexes.  NEW JOURNAL OF CHEMISTRY,  47  (9): (4472-4477).  [PMID:] [10.1039/D2NJ06145G]
4. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:] [10.1016/j.seppur.2022.122048]
5. Xiao-Yan Cao, Yuan-Zhe Ni, Jing Li, Ling Li, Yi-Lin Zhao, Gui-Peng Yang.  (2022)  Sorption and distribution performance of organophosphorus compound (Adenosine 5′-monophosphate)on marine sediments.  ENVIRONMENTAL POLLUTION,  311  (119993).  [PMID:35995290] [10.1016/j.envpol.2022.119993]
6. Amjad Hussain Memon, Bin Wei, Saira Shams, Yucui Jiang, Mengzhao Jiao, Mingming Su, Hao Liang.  (2022)  Construction of robust bienzyme-mimicking nanocatalysts for dye degradation by self-assembly of hematin, metal ions, and nucleotides.  Catalysis Science & Technology,  12  (9): (2846-2855).  [PMID:] [10.1039/D1CY01125A]
7. Yucui Jiang, Saixing Liu, Qipeng Yuan, Hao Liang.  (2021)  Zr-based acid-stable nucleotide coordination polymers: An excellent platform for acidophilic enzymes immobilization.  JOURNAL OF INORGANIC BIOCHEMISTRY,  216  (111338).  [PMID:33445108] [10.1016/j.jinorgbio.2020.111338]
8. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long.  (2020)  Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing.  MICROCHEMICAL JOURNAL,  159  (105417).  [PMID:] [10.1016/j.microc.2020.105417]
9. Saira Shams, Waqas Ahmad, Amjad Hussain Memon, Yun Wei, Qipeng Yuan, Hao Liang.  (2019)  Facile synthesis of laccase mimic Cu/H3BTC MOF for efficient dye degradation and detection of phenolic pollutants.  RSC Advances,  (70): (40845-40854).  [PMID:35540072] [10.1039/C9RA07473B]
10. Ting Zou, You Han, Xinxue Li, Wei Li, Jinli Zhang, Yan Fu.  (2019)  Unexpected catalytic activity of Pd(II)-coordinated nucleotides in hydrogenation reduction.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  560  (344).  [PMID:] [10.1016/j.colsurfa.2018.10.034]
11. Chunning Heng, Xin Zhou, Xiaoyan Zheng, Meiying Liu, Yuanqing Wen, Hongye Huang, Daidi Fan, Junfeng Hui, Xiaoyong Zhang, Yen Wei.  (2018)  Surface grafting of rare-earth ions doped hydroxyapatite nanorods (HAp:Ln(Eu/Tb)) with hydrophilic copolymers based on ligand exchange reaction: Biological imaging and cancer treatment.  Materials Science & Engineering C-Materials for Biological Applications,  91  (556).  [PMID:30033287] [10.1016/j.msec.2018.05.079]
12. Chunfang Li, Shuhui Jiang, Xinying Zhao, Hao Liang.  (2017)  Co-Immobilization of Enzymes and Magnetic Nanoparticles by Metal-Nucleotide Hydrogelnanofibers for Improving Stability and Recycling.  MOLECULES,  22  (1): (179).  [PMID:28125003] [10.3390/molecules22010179]
13. Hao Liang, Feifei Lin, Zijie Zhang, Biwu Liu, Shuhui Jiang, Qipeng Yuan, Juewen Liu.  (2017)  Multicopper Laccase Mimicking Nanozymes with Nucleotides as Ligands.  ACS Applied Materials & Interfaces,  (2): (1352–1360).  [PMID:28004568] [10.1021/acsami.6b15124]
14. Yihui Hu, Wenjing Guo, Yubin Ding, Hanjun Cheng, Hui Wei.  (2016)  Modulating luminescence of Tb3+ with biomolecules for sensing heparin and its contaminant OSCS.  BIOSENSORS & BIOELECTRONICS,  86  (858).  [PMID:27494809] [10.1016/j.bios.2016.07.085]
15. Hao Liang, Shuhui Jiang, Qipeng Yuan, Guofeng Li, Feng Wang, Zijie Zhang, Juewen Liu.  (2016)  Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection.  Nanoscale,  (11): (6071-6078).  [PMID:26932320] [10.1039/C5NR08734A]
16. Jian Sun, Bin Wang, Xue Zhao, Zong-Jun Li, Xiurong Yang.  (2016)  Fluorescent and Colorimetric Dual-Readout Assay for Inorganic Pyrophosphatase with Cu2+-Triggered Oxidation of o-Phenylenediamine.  ANALYTICAL CHEMISTRY,  88  (2): (1355–1361).  [PMID:26703206] [10.1021/acs.analchem.5b03848]

References

1. Liu Yujie, Gao Ran, Liu Xingcen, Zheng Jinhua, Wu Xia.  (2023)  High-efficiency fluorescent coordination polymer nanoparticles co-doped with Ce3+/Tb3+ ions for curcumin detection.  MICROCHIMICA ACTA,  190  (9): (1-11).  [PMID:37587349] [10.1007/s00604-023-05933-6]
2. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan.  (2023)  Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,  60  (69).  [PMID:] [10.1016/j.cjche.2023.01.009]
3. Chujing Yang, Zhiwei Zhang, Jingqi Chen, Xinying Zhang, Yankai Dai, Xuyi Li, Yingying Chen, Jiaqiang Xu, Lingyan Feng.  (2023)  Multiple switchable circularly polarized luminescence from nucleotide/terbium(III) complexes.  NEW JOURNAL OF CHEMISTRY,  47  (9): (4472-4477).  [PMID:] [10.1039/D2NJ06145G]
4. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan.  (2022)  Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine.  SEPARATION AND PURIFICATION TECHNOLOGY,  302  (122048).  [PMID:] [10.1016/j.seppur.2022.122048]
5. Xiao-Yan Cao, Yuan-Zhe Ni, Jing Li, Ling Li, Yi-Lin Zhao, Gui-Peng Yang.  (2022)  Sorption and distribution performance of organophosphorus compound (Adenosine 5′-monophosphate)on marine sediments.  ENVIRONMENTAL POLLUTION,  311  (119993).  [PMID:35995290] [10.1016/j.envpol.2022.119993]
6. Amjad Hussain Memon, Bin Wei, Saira Shams, Yucui Jiang, Mengzhao Jiao, Mingming Su, Hao Liang.  (2022)  Construction of robust bienzyme-mimicking nanocatalysts for dye degradation by self-assembly of hematin, metal ions, and nucleotides.  Catalysis Science & Technology,  12  (9): (2846-2855).  [PMID:] [10.1039/D1CY01125A]
7. Yucui Jiang, Saixing Liu, Qipeng Yuan, Hao Liang.  (2021)  Zr-based acid-stable nucleotide coordination polymers: An excellent platform for acidophilic enzymes immobilization.  JOURNAL OF INORGANIC BIOCHEMISTRY,  216  (111338).  [PMID:33445108] [10.1016/j.jinorgbio.2020.111338]
8. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long.  (2020)  Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing.  MICROCHEMICAL JOURNAL,  159  (105417).  [PMID:] [10.1016/j.microc.2020.105417]
9. Saira Shams, Waqas Ahmad, Amjad Hussain Memon, Yun Wei, Qipeng Yuan, Hao Liang.  (2019)  Facile synthesis of laccase mimic Cu/H3BTC MOF for efficient dye degradation and detection of phenolic pollutants.  RSC Advances,  (70): (40845-40854).  [PMID:35540072] [10.1039/C9RA07473B]
10. Ting Zou, You Han, Xinxue Li, Wei Li, Jinli Zhang, Yan Fu.  (2019)  Unexpected catalytic activity of Pd(II)-coordinated nucleotides in hydrogenation reduction.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  560  (344).  [PMID:] [10.1016/j.colsurfa.2018.10.034]
11. Chunning Heng, Xin Zhou, Xiaoyan Zheng, Meiying Liu, Yuanqing Wen, Hongye Huang, Daidi Fan, Junfeng Hui, Xiaoyong Zhang, Yen Wei.  (2018)  Surface grafting of rare-earth ions doped hydroxyapatite nanorods (HAp:Ln(Eu/Tb)) with hydrophilic copolymers based on ligand exchange reaction: Biological imaging and cancer treatment.  Materials Science & Engineering C-Materials for Biological Applications,  91  (556).  [PMID:30033287] [10.1016/j.msec.2018.05.079]
12. Chunfang Li, Shuhui Jiang, Xinying Zhao, Hao Liang.  (2017)  Co-Immobilization of Enzymes and Magnetic Nanoparticles by Metal-Nucleotide Hydrogelnanofibers for Improving Stability and Recycling.  MOLECULES,  22  (1): (179).  [PMID:28125003] [10.3390/molecules22010179]
13. Hao Liang, Feifei Lin, Zijie Zhang, Biwu Liu, Shuhui Jiang, Qipeng Yuan, Juewen Liu.  (2017)  Multicopper Laccase Mimicking Nanozymes with Nucleotides as Ligands.  ACS Applied Materials & Interfaces,  (2): (1352–1360).  [PMID:28004568] [10.1021/acsami.6b15124]
14. Yihui Hu, Wenjing Guo, Yubin Ding, Hanjun Cheng, Hui Wei.  (2016)  Modulating luminescence of Tb3+ with biomolecules for sensing heparin and its contaminant OSCS.  BIOSENSORS & BIOELECTRONICS,  86  (858).  [PMID:27494809] [10.1016/j.bios.2016.07.085]
15. Hao Liang, Shuhui Jiang, Qipeng Yuan, Guofeng Li, Feng Wang, Zijie Zhang, Juewen Liu.  (2016)  Co-immobilization of multiple enzymes by metal coordinated nucleotide hydrogel nanofibers: improved stability and an enzyme cascade for glucose detection.  Nanoscale,  (11): (6071-6078).  [PMID:26932320] [10.1039/C5NR08734A]
16. Jian Sun, Bin Wang, Xue Zhao, Zong-Jun Li, Xiurong Yang.  (2016)  Fluorescent and Colorimetric Dual-Readout Assay for Inorganic Pyrophosphatase with Cu2+-Triggered Oxidation of o-Phenylenediamine.  ANALYTICAL CHEMISTRY,  88  (2): (1355–1361).  [PMID:26703206] [10.1021/acs.analchem.5b03848]

Solution Calculators