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5′-Deoxyadenosine - ≥98%, high purity , CAS No.4754-39-6

  • ≥98%
Item Number
D350076
Grouped product items
SKUSizeAvailabilityPrice Qty
D350076-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$45.90
D350076-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$77.90
D350076-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$157.90
D350076-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$251.90
D350076-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$377.90

an analog of adenosin, and an intermediate in the degradation reaction of S-adenosylmethionine.

View related series
Nucleosides and nucleotides

Basic Description

Synonyms5'-deoxyadenosine|4754-39-6|ADENOSINE, 5'-DEOXY-|CHEBI:17319|2U0TYC8Y5A|(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol|5AD|(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol|5 inverted exclamation marka-dAdo|5?
Specifications & Purity≥98%
Biochemical and Physiological Mechanisms5 '- deoxyadenosine is a substrate of methylthioadenosine/S-adenosine homocysteine (MTA/SAH) nucleosidase in microorganisms. 5 '- deoxyadenosine is a byproduct of S-adenosylmethionine (SAM) cleavage. High levels of deoxyadenosine inhibit SAM dependent enz
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

5′-Deoxyadenosine is an analog of adenosin. In the degradation reaction of S-adenosylmethionine (SAM), 5′-Deoxyadenosine is an intermediate. 5′-Deoxyadenosine is used to study the enzyme kinematics of phosphomethylpyrimidine synthase, glutamate mutase, and 5′-methylthioadenosine phosphorylase. In addition, 5′-Deoxyadenosine has been used as a mass spectroscopy standard, and a thymidine phosphorylase activity screening inhibitor. Finally, 5′-Deoxyadenosine functions as a substrate if 5′-Deoxyadenosine deaminase (DadD) assay.

Product Properties

pKapKa: 13.29 (Predicted), pKa: 3.82 (Predicted)
Ki DataAdenosine A1 receptor: Ki= 269 nM (rat); Adenosine A2a receptor: Ki= 596 nM (rat); Adenosine A3 receptor: Ki= 2.83 μM (rat)

Associated Targets

HSPA8 Tchem Heat shock cognate 71 kDa protein 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MTAP Tchem S-methyl-5'-thioadenosine phosphorylase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA2A Tclin Adenosine receptor A2a 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA1 Tclin Adenosine receptor A1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ADORA3 Tchem Adenosine receptor A3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methyloxolane-3,4-diol
INCHI InChI=1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChi Key XGYIMTFOTBMPFP-KQYNXXCUSA-N
Canonical SMILES CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O
Isomeric SMILES C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O
WGK Germany 3
RTECS AU7358650
PubChem CID 439182
Molecular Weight 251.24

Certificates

Certificate of Analysis(COA)

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10 results found

Lot NumberCertificate TypeDateItem
G2410091Certificate of AnalysisMay 22, 2024 D350076
G2410118Certificate of AnalysisMay 22, 2024 D350076
G2410119Certificate of AnalysisMay 22, 2024 D350076
G2410120Certificate of AnalysisMay 22, 2024 D350076
G2410121Certificate of AnalysisMay 22, 2024 D350076
G2410288Certificate of AnalysisMay 22, 2024 D350076
G2410369Certificate of AnalysisMay 22, 2024 D350076
G2410370Certificate of AnalysisMay 22, 2024 D350076
G2410371Certificate of AnalysisMay 22, 2024 D350076
G2410372Certificate of AnalysisMay 22, 2024 D350076

Chemical and Physical Properties

SolubilitySoluble in water (19.60 - 20.40 m mg/ml).
Refractive Indexn20D1.87 (Predicted)
Boil Point(°C)595.0° C at 760 mmHg (Predicted)
Melt Point(°C)203-205° C

Safety and Hazards(GHS)

WGK Germany 3
RTECS AU7358650

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Solution Calculators