Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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D350076-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $45.90 | |
D350076-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $77.90 | |
D350076-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $157.90 | |
D350076-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $251.90 | |
D350076-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $377.90 |
an analog of adenosin, and an intermediate in the degradation reaction of S-adenosylmethionine.
Synonyms | 5'-deoxyadenosine|4754-39-6|ADENOSINE, 5'-DEOXY-|CHEBI:17319|2U0TYC8Y5A|(2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-methyltetrahydrofuran-3,4-diol|5AD|(2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methyl-tetrahydrofuran-3,4-diol|5 inverted exclamation marka-dAdo|5? |
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Specifications & Purity | ≥98% |
Biochemical and Physiological Mechanisms | 5 '- deoxyadenosine is a substrate of methylthioadenosine/S-adenosine homocysteine (MTA/SAH) nucleosidase in microorganisms. 5 '- deoxyadenosine is a byproduct of S-adenosylmethionine (SAM) cleavage. High levels of deoxyadenosine inhibit SAM dependent enz |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Product Description | 5′-Deoxyadenosine is an analog of adenosin. In the degradation reaction of S-adenosylmethionine (SAM), 5′-Deoxyadenosine is an intermediate. 5′-Deoxyadenosine is used to study the enzyme kinematics of phosphomethylpyrimidine synthase, glutamate mutase, and 5′-methylthioadenosine phosphorylase. In addition, 5′-Deoxyadenosine has been used as a mass spectroscopy standard, and a thymidine phosphorylase activity screening inhibitor. Finally, 5′-Deoxyadenosine functions as a substrate if 5′-Deoxyadenosine deaminase (DadD) assay. |
pKa | pKa: 13.29 (Predicted), pKa: 3.82 (Predicted) |
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Ki Data | Adenosine A1 receptor: Ki= 269 nM (rat); Adenosine A2a receptor: Ki= 596 nM (rat); Adenosine A3 receptor: Ki= 2.83 μM (rat) |
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IUPAC Name | (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-methyloxolane-3,4-diol |
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INCHI | InChI=1S/C10H13N5O3/c1-4-6(16)7(17)10(18-4)15-3-14-5-8(11)12-2-13-9(5)15/h2-4,6-7,10,16-17H,1H3,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1 |
InChi Key | XGYIMTFOTBMPFP-KQYNXXCUSA-N |
Canonical SMILES | CC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)O |
Isomeric SMILES | C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)O |
WGK Germany | 3 |
RTECS | AU7358650 |
PubChem CID | 439182 |
Molecular Weight | 251.24 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2410091 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410118 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410119 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410120 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410121 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410288 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410369 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410370 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410371 | Certificate of Analysis | May 22, 2024 | D350076 |
G2410372 | Certificate of Analysis | May 22, 2024 | D350076 |
Solubility | Soluble in water (19.60 - 20.40 m mg/ml). |
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Refractive Index | n20D1.87 (Predicted) |
Boil Point(°C) | 595.0° C at 760 mmHg (Predicted) |
Melt Point(°C) | 203-205° C |
WGK Germany | 3 |
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RTECS | AU7358650 |