5-Hexynoic Acid-NHS Ester - 98%, high purity , CAS No.906564-59-8

Item Number

H596952

Grouped product items
SKU	Size	Availability	Price
H596952-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$856.90
H596952-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,621.90
H596952-500mg	500mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,341.90

Non-PEG linker

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Basic Description

Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	5-Hexynoic Acid-NHS Ester contains a propargyl group and an NHS ester group. This reagent is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Names and Identifiers

IUPAC Name	(2,5-dioxopyrrolidin-1-yl) hex-5-ynoate
INCHI	InChI=1S/C10H11NO4/c1-2-3-4-5-10(14)15-11-8(12)6-7-9(11)13/h1H,3-7H2
InChi Key	CXSSWEBEHUYETJ-UHFFFAOYSA-N
Canonical SMILES	C#CCCCC(=O)ON1C(=O)CCC1=O
Isomeric SMILES	C#CCCCC(=O)ON1C(=O)CCC1=O
PubChem CID	59805478
Molecular Weight	209.2

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation
Precautionary Statements	P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P264:Wash hands [and …] thoroughly after handling. P337+P313:IF eye irritation persists: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P332+P313:IF SKIN irritation occurs: Get medical advice/attention.

Citations of This Product

1. He Ji-Xiang, Fei Zheng-Cong, Fu Ling, Tian Cai-Ping, He Fu-Chu, Chi Hao, Yang Jing. (2022) A modification-centric assessment tool for the performance of chemoproteomic probes. Nature Chemical Biology, 18 (8): (904-912). [PMID:35864333] [10.1038/s41589-022-01074-8]

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Basic Description