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5-Hydroxy-L-tryptophan - 99%, high purity , CAS No.4350-09-8, Inhibitor of Proton-coupled Amino acid Transporter 1;Inhibitor of Proton-coupled Amino acid Transporter 2

  • Moligand™
  • ≥99%
Item Number
H111084
Grouped product items
SKUSizeAvailabilityPrice Qty
H111084-250mg
250mg
In stock
$9.90
H111084-1g
1g
In stock
$14.90
H111084-5g
5g
In stock
$46.90
H111084-25g
25g
In stock
$209.90
H111084-100g
100g
In stock
$754.90
H111084-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$3,393.90

Serotonin precursor

Basic Description

Synonyms5-hydroxy-L-tryptophan|L-5-Hydroxytryptophan|oxitriptan|4350-09-8|5-hydroxytryptophan|Levothym|Cincofarm|L-5-Htp|Pretonine|Oxyfan|Quietim|Levotinine|Serotonyl|Telesol|Triptene|5-Hydroxytryptophan L-form|hydroxytryptophan|(2S)-2-amino-3-(5-hydroxy-1H-indol
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsHydroxylation of L-tryptophan occurs in the brain during serotonin synthesis. This is a step that controls the production of serotonin and also yields 5-hydroxy-l-tryptophan (5-HTP) as a metabolite. Thus, consumption 5-HTP, increases the serotonin level,
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of Proton-coupled Amino acid Transporter 1;Inhibitor of Proton-coupled Amino acid Transporter 2
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

5-Hydroxy-L-tryptophan has been used:

· to inject experimental mice for serotonin detection

· as a precursor of 5-hydroxytryptamine and injected in pregnant mice and neonatal rats for vital neutral red staining of lung slices

· as a standard in citrate-acetate buffer for its use in high performance liquid chromatography (HPLC) analysis

Names and Identifiers

Pubchem Sid488189742
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488189742
IUPAC Name (2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
INCHI InChI=1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)/t9-/m0/s1
InChi Key LDCYZAJDBXYCGN-VIFPVBQESA-N
Canonical SMILES C1=CC2=C(C=C1O)C(=CN2)CC(C(=O)O)N
Isomeric SMILES C1=CC2=C(C=C1O)C(=CN2)C[C@@H](C(=O)O)N
WGK Germany 3
RTECS YN7110000
PubChem CID 439280
UN Number 2811
Packing Group I
Molecular Weight 220.22
Beilstein 88200
Reaxy-Rn 88200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

16 results found

Lot NumberCertificate TypeDateItem
E1924019Certificate of AnalysisMar 10, 2023 H111084
K2228244Certificate of AnalysisDec 09, 2022 H111084
E23101046Certificate of AnalysisDec 01, 2022 H111084
E23101049Certificate of AnalysisDec 01, 2022 H111084
E23101053Certificate of AnalysisDec 01, 2022 H111084
E23101059Certificate of AnalysisDec 01, 2022 H111084
E23101068Certificate of AnalysisDec 01, 2022 H111084
E23101083Certificate of AnalysisDec 01, 2022 H111084
E23101089Certificate of AnalysisDec 01, 2022 H111084
E23101107Certificate of AnalysisDec 01, 2022 H111084
E23101122Certificate of AnalysisDec 01, 2022 H111084
E23101127Certificate of AnalysisDec 01, 2022 H111084
G2225033Certificate of AnalysisJul 29, 2022 H111084
G2225032Certificate of AnalysisJul 26, 2022 H111084
G2220397Certificate of AnalysisSep 04, 2021 H111084
I2206038Certificate of AnalysisSep 04, 2021 H111084

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Chemical and Physical Properties

Solubility insoluble in EtOH; ≥10.42 mg/mL in H2O; ≥51.9 mg/mL in DMSO
Refractive Index1.4850
Specific Rotation[α]-33 ° (C=1, H2O)
Melt Point(°C)270°C

Safety and Hazards(GHS)

Pictogram(s) GHS06
Signal Danger
Hazard Statements

H319:Causes serious eye irritation

H302:Harmful if swallowed

H226:Flammable liquid and vapor

H332:Harmful if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378:In case of fire: Use ... to extinguish.

P210:Keep away from heat, hot surface, sparks, open flames and other ignition sources. - No smoking.

P501:Dispose of contents/container to ...

P233:Keep container tightly closed.

P240:Ground/bond container and receiving equipment.

P264:Wash hands [and …] thoroughly after handling.

P403+P235:Store in a well-ventilated place. Keep cool.

P303+P361+P353:IF ON SKIN (or hair): Take off Immediately all contaminated clothing. Rinse SKIN with water [or shower].

P271:Use only outdoors or in a well-ventilated area.

P241:Use explosion-proof [electrical/ventilating/lighting/.../] equipment.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P330:Rinse mouth.

P242:Use only non-sparking tools.

P243:Take precautionary measures against static discharge.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P301+P317:IF SWALLOWED: Get medical help.

P317:Get emergency medical help.

P337+P317:If eye irritation persists: Get medical help.

WGK Germany 3
RTECS YN7110000
Reaxy-Rn 88200
Class 6.1
Merck Index 4847

Related Documents

References

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