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G protein-coupled receptors (GPCRs)
Angiotensin receptors
5-oxo-1-2-4-oxadiazol biphenyl , CAS No.O607236, Antagonist of AT 1 receptor

5-oxo-1-2-4-oxadiazol biphenyl , CAS No.O607236, Antagonist of AT 1 receptor

Item Number

O607236

Grouped product items
SKU	Size	Availability	Price	Qty
O607236-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,190.90
O607236-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,334.90

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Basic Description

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	(2S)-2-[[4-[2-(5-oxo-2H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]methyl-propanoylamino]pentanoic acid
INCHI	InChI=1S/C23H25N3O5/c1-3-7-19(22(28)29)26(20(27)4-2)14-15-10-12-16(13-11-15)17-8-5-6-9-18(17)21-24-23(30)31-25-21/h5-6,8-13,19H,3-4,7,14H2,1-2H3,(H,28,29)(H,24,25,30)/t19-/m0/s1
InChi Key	FXELTRKWYHPHAE-IBGZPJMESA-N
Canonical SMILES	CCC[C@H](N(C(=O)CC)Cc1ccc(cc1)c1ccccc1c1noc(=O)[nH]1)C(=O)O
PubChem CID	136218976

PubChem CID	136218976
GPCRdb Ligand	5-oxo-1-2-4-oxadiazol biphenyl

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1. Nie YY, Da YJ, Zheng H, Yang XX, Jia L, Wen CH, Liang LS, Tian J, Chen ZL. (2012) Synthesis and biological evaluation of novel potent angiotensin II receptor antagonists with anti-hypertension effect.. Bioorg Med Chem, 20 (8): (2747-61). [PMID:22410249]

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