C2314499Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | 2199-87-3|6-bromo-2-oxo-2H-chromene-3-carboxylic acid|6-Bromocoumarin-3-carboxylic acid|UBP608|6-bromo-2-oxochromene-3-carboxylic acid|MFCD00047640|6-Bromo-3-carboxycoumarin|CHEMBL2333943|Maybridge1_000837|6-bromo-3-carboxy-coumarin|Oprea1_401589|AN-512/1 |
|---|---|
| Specifications & Purity | ≥97% |
| Biochemical and Physiological Mechanisms | UBP608 is NMDA receptor family allosteric modulator that selectively inhibits GluN1/GluN2A receptors with a 23-fold selectivity compared to GluN1/GluN2D receptors. It appears to distinguish between GluN2A and GluN2B, and between GluN2C and GluN2D. UBP608 |
| Shipped In | Normal |
| Note | 卖完停产，不再备货 |
| Product Description | A chemical that acts on NMDA receptor subtypes Glu1/Glu2 |
Associated Targets
GPR35 Tchem G-protein coupled receptor 35 0 Activities
GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 0 Activities
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GRIN2A Tclin Glutamate receptor ionotropic, NMDA 2A 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIN2B Tclin Glutamate receptor ionotropic, NMDA 2B 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIN2C Tclin Glutamate receptor ionotropic, NMDA 2C 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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GRIN2D Tclin Glutamate receptor ionotropic, NMDA 2D 0 Activities
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Names and Identifiers
| Pubchem Sid | 488191168 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488191168 |
| IUPAC Name | 6-bromo-2-oxochromene-3-carboxylic acid |
| INCHI | InChI=1S/C10H5BrO4/c11-6-1-2-8-5(3-6)4-7(9(12)13)10(14)15-8/h1-4H,(H,12,13) |
| InChi Key | XFQHPAXNKDYMOX-UHFFFAOYSA-N |
| Canonical SMILES | C1=CC2=C(C=C1Br)C=C(C(=O)O2)C(=O)O |
| Isomeric SMILES | C1=CC2=C(C=C1Br)C=C(C(=O)O2)C(=O)O |
| WGK Germany | 3 |
| PubChem CID | 694463 |
| Molecular Weight | 269.05 |
| Beilstein | 13960 |
Certificates
Certificate of Analysis(COA)
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Chemical and Physical Properties
| Melt Point(°C) | 193 °C |
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Safety and Hazards(GHS)
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |