Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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SKU | Size | Availability | Price | Qty |
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C105327-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $27.90 | |
C105327-100mg | 100mg | In stock | $90.90 | |
C105327-250mg | 250mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $204.90 | |
C105327-500mg | 500mg | In stock | $247.90 | |
C105327-1g | 1g | In stock | $446.90 | |
C105327-5g | 5g | In stock | $2,008.90 | |
C105327-25g | 25g | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $9,039.90 |
Amine-reactive fluorescent label
Synonyms | 6-Carboxyfluorescein | 3301-79-9 | 6-FAM | MFCD00036873 | JHJ853P6SM | 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid | CHEBI:39073 | 3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxylic acid | Spiro[isobenzofuran-1(3H),9'-[9 |
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Specifications & Purity | ≥95% |
Biochemical and Physiological Mechanisms | Amine-reactive fluorescent label. 5-FAM isomer. 6-CFDA and 6-CFDA N -succinimidyl ester hydrolytic product. Polar tracer. Covalently labels peptides and proteins. Deprotonates below pH 7 resulting in reduced fluoresc |
Storage Temp | Protected from light,Store at -20°C |
Shipped In | Ice chest + Ice pads |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | 6-Carboxyfluorescein, or 6-FAM is a fluorescent dye primarily utilized in labeling nucleotides and nucleic acids. Also useful as a starting material for the synthesis of other fluorescein-derived reagents. |
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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IUPAC Name | 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylic acid |
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INCHI | InChI=1S/C21H12O7/c22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h1-9,22-23H,(H,24,25) |
InChi Key | BZTDTCNHAFUJOG-UHFFFAOYSA-N |
Canonical SMILES | C1=CC2=C(C=C1C(=O)O)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O |
Isomeric SMILES | C1=CC2=C(C=C1C(=O)O)C3(C4=C(C=C(C=C4)O)OC5=C3C=CC(=C5)O)OC2=O |
WGK Germany | 3 |
PubChem CID | 76806 |
Molecular Weight | 376.32 |
Beilstein | 54341 |
Reaxy-Rn | 54341 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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G2403242 | Certificate of Analysis | Apr 13, 2024 | C105327 |
L1910174 | Certificate of Analysis | Sep 11, 2023 | C105327 |
C2404222 | Certificate of Analysis | Jun 15, 2022 | C105327 |
G2222137 | Certificate of Analysis | Jun 15, 2022 | C105327 |
G2222146 | Certificate of Analysis | Jun 15, 2022 | C105327 |
G2222157 | Certificate of Analysis | Jun 15, 2022 | C105327 |
G2222158 | Certificate of Analysis | Jun 15, 2022 | C105327 |
G2222202 | Certificate of Analysis | Jun 15, 2022 | C105327 |
H2307931 | Certificate of Analysis | Jun 15, 2022 | C105327 |
L2306051 | Certificate of Analysis | Jun 15, 2022 | C105327 |
Solubility | 0.1 M NaOH: 9.80-10.20 mg/mL, clear to slightly hazy, orange |
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Sensitivity | Light sensitive. |
Melt Point(°C) | 150°C |
Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell. |
WGK Germany | 3 |
Reaxy-Rn | 54341 |
1. Qiang Chen, Lili Zheng, Xiaoqin Deng, Menghan Zhang, Wendi Han, Zhengjun Huang, Chenfang Miao, Shaohuang Weng. (2023) A fluorescence biosensor for tyrosinase activity analysis based on silicon-doped carbon quantum dots. CHEMICAL & PHARMACEUTICAL BULLETIN, (4): [PMID:37704432] |
2. Li X, Qiao Y, Wang X, Ma R, Li T, Zhang Y, Borris RP.. (2019) Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3.. J Nat Prod, 82 (4): (832-839). [PMID:30892891] |
1. Qiang Chen, Lili Zheng, Xiaoqin Deng, Menghan Zhang, Wendi Han, Zhengjun Huang, Chenfang Miao, Shaohuang Weng. (2023) A fluorescence biosensor for tyrosinase activity analysis based on silicon-doped carbon quantum dots. CHEMICAL & PHARMACEUTICAL BULLETIN, (4): [PMID:37704432] |
2. Li X, Qiao Y, Wang X, Ma R, Li T, Zhang Y, Borris RP.. (2019) Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3.. J Nat Prod, 82 (4): (832-839). [PMID:30892891] |