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6-Hydroxy-5,7-dimethoxyflavone , CAS No.H607252, Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D
Basic Description Synonyms 6-Hydroxy-5,7-dimethoxyflavone|119892-40-9|UFM24|6-hydroxy-5,7-dimethoxy-2-phenyl-4H-chromen-4-one|CHEMBL464108|GTPL9878|UFM-24|DTXSID50559538|BDBM50250570|6-Hydroxy-5,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one Specifications & Purity Moligand™ Grade Moligand™ Action Type INHIBITOR Mechanism of action Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D
Names and Identifiers INCHI InChI=1S/C17H14O5/c1-20-14-9-13-15(17(21-2)16(14)19)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3 InChi Key YLSUKCVZCXUJBF-UHFFFAOYSA-N Canonical SMILES COc1cc2oc(cc(=O)c2c(c1O)OC)c1ccccc1 Isomeric SMILES COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)OC)O PubChem CID 14372618
References 1. Hsu YM, Wu TY, Du YC, El-Shazly M, Beerhues L, Thang TD, Van Luu H, Hwang TL, Chang FR, Wu YC. (2016) 3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity.. Phytochemistry, 122 (3): (184-192). [PMID:26732672 ] 2. Tsai YF, Chu TC, Chang WY, Wu YC, Chang FR, Yang SC, Wu TY, Hsu YM, Chen CY, Chang SH et al. . (2017) 6-Hydroxy-5,7-dimethoxy-flavone suppresses the neutrophil respiratory burst via selective PDE4 inhibition to ameliorate acute lung injury.. Free Radic Biol Med, 106 (3): (379-392). [PMID:28263828 ]
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