6-HydroxyDopamineHydrochloride

Item Number

H754215

Grouped product items
SKU	Size	Availability	Price
H754215-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$79.90
H754215-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$95.90
H754215-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$159.90

Basic Description

Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Neurotoxin that destroys catecholaminergic terminals.
Storage Temp	Store at 2-8°C,Protected from light,Argon charged
Shipped In	Wet ice
Product Description	6-Hydroxydopamine hydrochloride is a selective catecholaminergic neurotoxin. 6-Hydroxydopamine hydrochloride depletes brain catecholamine levels via uptake and accumulation by a transport mechanism specific to these neurons. Causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats, producing an animal model of Parkinson's disease. A selective catecholaminergic neurotoxin.

Names and Identifiers

IUPAC Name	5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride
INCHI	InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
InChi Key	QLMRJHFAGVFUAC-UHFFFAOYSA-N
Canonical SMILES	C1=C(C(=CC(=C1O)O)O)CCN.Cl
Isomeric SMILES	C1=C(C(=CC(=C1O)O)O)CCN.Cl
WGK Germany	3
RTECS	DC4650000
PubChem CID	160157
Molecular Weight	205.64
Beilstein	4274007

Solubility

Soluble in water (>50 mg/ml).

Sensitivity

Hygroscopic；Light sensitive

Melt Point(°C)

232-233 °C

Safety and Hazards(GHS)

Pictogram(s)	GHS07
Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P319:Get medical help if you feel unwell.
WGK Germany	3
RTECS	DC4650000

Solution Calculators

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Basic Description