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6-Hydroxyflavanone - 97%, high purity , CAS No.4250-77-5

  • ≥97%
Item Number
H157359
Grouped product items
SKUSizeAvailabilityPrice Qty
H157359-250mg
250mg
In stock
$14.90
H157359-1g
1g
In stock
$43.90
H157359-5g
5g
In stock
$128.90

Basic Description

Synonyms6-Hydroxyflavanone|4250-77-5|6-hydroxy-2-phenylchroman-4-one|6-hydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one|Flavanone, 6-hydroxy-|(+/-)-6-Hydroxyflavanone|6-hydroxy-2-phenyl-2,3-dihydrochromen-4-one|4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy-2-phenyl-|
Specifications & Purity≥97%
Shipped InNormal
Product Description

Product Describtion:

6-Hydroxyflavanone is a flavonoid.Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio.It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.


Product Application:

6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.

Associated Targets

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B1 Tchem Estradiol 17-beta-dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B2 Tchem Estradiol 17-beta-dehydrogenase 2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

Pubchem Sid488192608
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488192608
IUPAC Name 6-hydroxy-2-phenyl-2,3-dihydrochromen-4-one
INCHI InChI=1S/C15H12O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-8,15-16H,9H2
InChi Key XYHWPQUEOOBIOW-UHFFFAOYSA-N
Canonical SMILES C1C(OC2=C(C1=O)C=C(C=C2)O)C3=CC=CC=C3
Isomeric SMILES C1C(OC2=C(C1=O)C=C(C=C2)O)C3=CC=CC=C3
WGK Germany 3
PubChem CID 2734580
Molecular Weight 240.26
Beilstein 18(3/4)632
Reaxy-Rn 87354

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
F2302494Certificate of AnalysisJun 10, 2023 H157359
F2302495Certificate of AnalysisJun 10, 2023 H157359
F2302499Certificate of AnalysisJun 10, 2023 H157359
F2302503Certificate of AnalysisJun 10, 2023 H157359
F2302505Certificate of AnalysisJun 10, 2023 H157359
F2302497Certificate of AnalysisJun 10, 2023 H157359

Chemical and Physical Properties

Melt Point(°C)219-222°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 87354

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Solution Calculators