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6-Hydroxyflavone - >98.0%, high purity , CAS No.6665-83-4

  • ≥98%
Item Number
H157351
Grouped product items
SKUSizeAvailabilityPrice Qty
H157351-250mg
250mg
In stock
$9.90
H157351-1g
1g
In stock
$27.90
H157351-5g
5g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$105.90
H157351-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$474.90

Discover 6-Hydroxyflavone by Aladdin Scientific in >98.0% for only $9.90. Available - in Ligands at Aladdin Scientific. Tags: Phenylpropanoids, Six-Membered Heterocyclic Compounds.

Basic Description

Synonyms6-Hydroxyflavone|6665-83-4|6-hydroxy-2-phenylchromen-4-one|6-Hydroxy-2-phenyl-4H-chromen-4-one|6-Hydroxy-2-phenyl-4-benzopyrone|6-Monohydroxyflavone|6-Hydroxy-2-phenyl-chromen-4-one|NSC-26744|MLS000738065|4H-1-Benzopyran-4-one, 6-hydroxy-2-phenyl-|CHEMBL1
Specifications & Purity>98.0%
Shipped InNormal

Names and Identifiers

IUPAC Name 6-hydroxy-2-phenylchromen-4-one
INCHI InChI=1S/C15H10O3/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9,16H
InChi Key GPZYYYGYCRFPBU-UHFFFAOYSA-N
Canonical SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O
Isomeric SMILES C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)O
WGK Germany 3
PubChem CID 72279
Molecular Weight 238.24
Reaxy-Rn 15827

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

Melt Point(°C)234-236 °C (lit.)

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 15827

Related Documents

References

1. Ricardo Q Aucelio,Juliana M Carvalho,Juliana T Real,Luis Maqueira-Espinosa,Aurora Pérez-Gramatges,Andrea R da Silva.  (2016-04-24)  Study of the interaction of flavonoids with 3-mercaptopropionic acid modified CdTe quantum dots mediated by cetyltrimethyl ammonium bromide in aqueous medium..  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy,  172  (147-155).  [PMID:27106812]
2. Hui Cao,Xiaojuan Liu,Nataša Poklar Ulrih,Pradeep K Sengupta,Jianbo Xiao.  (2018-09-04)  Plasma protein binding of dietary polyphenols to human serum albumin: A high performance affinity chromatography approach..  Food chemistry,  270  (257-263).  [PMID:30174044]
3. Hye-Jeong Hwang,Inseong Choi,Young-Jin Kim,Young-Kwan Kim,Woon-Seok Yeo.  (2018-10-07)  Immobilization of phenol-containing molecules on self-assembled monolayers on gold via surface chemistry..  Colloids and surfaces. B, Biointerfaces,  173  (164-170).  [PMID:30292024]
4. Sourav Das,Santanu Santra,Mostofa Ataur Rohman,Mahuah Ray,Madhurima Jana,Atanu Singha Roy.  (2018-10-14)  An insight into the binding of 6-hydroxyflavone with hen egg white lysozyme: a combined approach of multi-spectroscopic and computational studies..  Journal of biomolecular structure & dynamics,  37  ((15)): (4019-4034).  [PMID:30314416]
5. Angélica Flores-Flores,Samuel Estrada-Soto,César Millán-Pacheco,Blanca Bazán-Perkins,Rafael Villalobos-Molina,Leticia Moreno-Fierros,Rogelio Hernández-Pando,Sara García-Jiménez,Julio César Rivera-Leyva.  (2018-11-06)  Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6-hydroxyflavone..  Drug development research,  80  ((2)): (218-229).  [PMID:30394554]
6. Jie Bai,Shengyu Zhao,Xiaoqing Fan,Yonghui Chen,Xiaowen Zou,Minwan Hu,Baolian Wang,Jing Jin,Xiaojian Wang,Jinping Hu,Dan Zhang,Yan Li.  (2019-02-23)  Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships..  Toxicology and applied pharmacology,  369  (49-59).  [PMID:30790579]
7. Xiaoqing Fan,Jie Bai,Minwan Hu,Yanxia Xu,Shengyu Zhao,Yanhong Sun,Baolian Wang,Jinping Hu,Yan Li.  (2020-04-08)  Drug interaction study of flavonoids toward OATP1B1 and their 3D structure activity relationship analysis for predicting hepatoprotective effects..  Toxicology,  437  (152445-152445).  [PMID:32259555]
8. Richard Lantz,Brian Busbee,Ewa P Wojcikiewicz,Deguo Du.  (2020-05-28)  Flavonoids with Vicinal Hydroxyl Groups Inhibit Human Calcitonin Amyloid Formation..  Chemistry (Weinheim an der Bergstrasse, Germany),  26  ((57)): (13063-13071).  [PMID:32458489]
9. Sinjan Das,Shounak Mukherjee,Suman Chakrabarty,Nitin Chattopadhyay.  (2020-11-10)  Hydroxyl Group-Directed Solvation of Excited-State Intramolecular Proton Transfer Probes in Water: A Demonstration from the Fluorescence Anisotropy of Hydroxyflavones..  The journal of physical chemistry. A,  125  ((1)): (57-64).  [PMID:33166155]
10. Chien-Hung Lai,Yu-Wei Wu,Shauh-Der Yeh,Yu-Hsaing Lin,Yu-Hui Tsai.  (2014-05-06)  Effects of 6-Hydroxyflavone on Osteoblast Differentiation in MC3T3-E1 Cells..  Evidence-based complementary and alternative medicine : eCAM,  2014  (924560-924560).  [PMID:24795772]
11. Xing Wang,Zhiwei Wang,Preetpal Singh Sidhu,Umesh R Desai,Qibing Zhou.  (2015-03-20)  6-Hydroxyflavone and derivatives exhibit potent anti-inflammatory activity among mono-, di- and polyhydroxylated flavones in kidney mesangial cells..  PloS one,  10  ((3)): (e0116409-e0116409).  [PMID:25790236]
12. Tomohide Uno,Chika Ogura,Chiho Izumi,Masahiko Nakamura,Takeshi Yanase,Hiroshi Yamazaki,Hitoshi Ashida,Kengo Kanamaru,Hiroshi Yamagata,Hiromasa Imaishi.  (2015-07-30)  Point mutation of cytochrome P450 2A6 (a polymorphic variant CYP2A6.25) confers new substrate specificity towards flavonoids..  Biopharmaceutics & drug disposition,  36  ((8)): (552-563).  [PMID:26222491]
13. Zia Ud Din,Syed Umer Farooq,Muhammad Shahid,Osama Alghamdi,Nawwaf Al-Hamoudi,Fahim Vohra,Tariq Abduljabbar.  (2020-09-11)  The flavonoid 6-hydroxyflavone prevention of cisplatin-induced nephrotoxicity..  Histology and histopathology,  35  ((10)): (1197-1209).  [PMID:32909617]

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