6-Hydroxynicotinic Acid - 98%, high purity , CAS No.5006-66-6

  • ≥98%
Item Number
H108017
Grouped product items
SKUSizeAvailabilityPrice Qty
H108017-5g
5g
In stock
$15.90
H108017-10g
10g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$23.90
H108017-25g
25g
In stock
$45.90
H108017-100g
100g
In stock
$138.90
H108017-500g
500g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$624.90

Basic Description

Synonyms6-oxonicotinic acid | NSC53377 | NSC-53377 | W-105987 | 2-Hydroxy-5-carboxypyridine | EN300-21525 | SR-01000945209-1 | 6-Oxo-1,6-dihydro-3-pyridinecarboxylic acid # | FT-0659077 | STK687617 | BS-3788 | AM20061258 | 6-HYDROXYNICOTINIC ACID [USP-RS] | indox
Specifications & Purity≥98%
Shipped InNormal

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

Pubchem Sid488184742
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488184742
IUPAC Name 6-oxo-1H-pyridine-3-carboxylic acid
INCHI InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChi Key BLHCMGRVFXRYRN-UHFFFAOYSA-N
Canonical SMILES C1=CC(=O)NC=C1C(=O)O
Isomeric SMILES C1=CC(=O)NC=C1C(=O)O
WGK Germany 3
PubChem CID 72924
Molecular Weight 139.11
Beilstein 22215
Reaxy-Rn 115991

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot NumberCertificate TypeDateItem
K1920080Certificate of AnalysisSep 06, 2023 H108017
G1918057Certificate of AnalysisMay 08, 2023 H108017
C2313281Certificate of AnalysisJan 02, 2023 H108017
C2313282Certificate of AnalysisJan 02, 2023 H108017
C2313283Certificate of AnalysisJan 02, 2023 H108017
C2313284Certificate of AnalysisJan 02, 2023 H108017
C2313285Certificate of AnalysisJan 02, 2023 H108017
C2313286Certificate of AnalysisJan 02, 2023 H108017
C2313287Certificate of AnalysisJan 02, 2023 H108017

Chemical and Physical Properties

Melt Point(°C)300°C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3
Reaxy-Rn 115991

Related Documents

Citations of This Product

1. Zhi Chen, Zhaohe Dong, Xin Ju, Lishi Yan, Liangzhi Li, Donzhi Wei.  (2023)  Screening of a novel and thermostable nicotinate dehydrogenase-producing strain Bacillus paramycoides for efficient synthesis of 6-hydroxynicotinic acid.  BIOCATALYSIS AND BIOTRANSFORMATION,      [PMID:22383884] [10.1080/10242422.2023.2289338]
2. Yu-Ting Shang, Jiufu Qin, Jin-Song Gong, Zi-Kai Wang, Heng Li, Hui Li, Jin-Song Shi, Zheng-Hong Xu.  (2021)  High-throughput screening of a nicotinate dehydrogenase producing Pseudomonas putida mutant for efficient biosynthesis of 6-hydroxynicotinic acid.  Molecular Catalysis,  509  (111600).  [PMID:] [10.1016/j.mcat.2021.111600]
3. Hu Xiaopeng, Xia Yide, Liu Yiwei, Zhao Faqiong, Zeng Baizhao.  (2021)  Determination of patulin using dual-dummy templates imprinted electrochemical sensor with PtPd decorated N-doped porous carbon for amplification.  MICROCHIMICA ACTA,  188  (5): (1-9).  [PMID:33797604] [10.1007/s00604-021-04812-2]
4. Hu Chunhui, Zhao Shuxue, Li Kuiran, Yu Hao.  (2019)  Microbial Degradation of Nicotinamide by a Strain Alcaligenes sp. P156.  Scientific Reports,  (1): (1-11).  [PMID:30842479] [10.1038/s41598-019-40199-0]
5. Wengang Zhang, Yong Han, Xiumei Chen, Xueli Luo, Jianlong Wang, Tianli Yue, Zhonghong Li.  (2017)  Surface molecularly imprinted polymer capped Mn-doped ZnS quantum dots as a phosphorescent nanosensor for detecting patulin in apple juice.  FOOD CHEMISTRY,  232  (145).  [PMID:28490057] [10.1016/j.foodchem.2017.03.156]

References

1. C L Kitts,J P Lapointe,V T Lam,R A Ludwig.  (1992-12-01)  Elucidation of the complete Azorhizobium nicotinate catabolism pathway..  Journal of bacteriology,  174  ((23)): (7791-7797).  [PMID:1447145]
2. S Shiraishi,N Sakamoto,K Maeda,T Ohki,M Hosoi,K Ohta,N Yamanaka.  (1985-02-27)  Availability of 6-hydroxynicotinic acid for rapid identification of Pseudomonas aeruginosa and Serratia marcescens..  Journal of chromatography,  338  ((1)): (51-59).  [PMID:3926801]
3. R A Ludwig.  (1986-01-01)  Rhizobium sp. strain ORS571 grows synergistically on N2 and nicotinate as N sources..  Journal of bacteriology,  165  ((1)): (304-307).  [PMID:3753598]
4. C M Puah,G Williams,R Ghanadian.  (1982-01-01)  Urinary unconjugated 5 alpha-androstane-3 alpha, 17 beta-diol in patients with prostatic tumours..  Urological research,  10  ((2)): (81-84).  [PMID:6180540]
5. David W Nyman,M Suzanne Stratton,Michael J Kopplin,Bruce L Dalkin,Raymond B Nagle,A Jay Gandolfi.  (2004-03-26)  Selenium and selenomethionine levels in prostate cancer patients..  Cancer detection and prevention,  28  ((1)): (8-16).  [PMID:15041072]
6. Ashish Gupta,Mayank Dwivedi,G A Nagana Gowda,Archana Ayyagari,A A Mahdi,M Bhandari,C L Khetrapal.  (2005-03-11)  (1)H NMR spectroscopy in the diagnosis of Pseudomonas aeruginosa-induced urinary tract infection..  NMR in biomedicine,  18  ((5)): (293-299).  [PMID:15759292]
7. Li Xu,Sheng Yuan,Ting Chen,Yi-jun Dai.  (2006-04-04)  [Combination of growing culture transformation and resting cells transformation of Pseudomonas putida NA-1 for production of 6-hydroxynicotinic acid]..  Wei sheng wu xue bao = Acta microbiologica Sinica,  46  ((1)): (63-67).  [PMID:16579467]
8. Timothy J Key,Paul N Appleby,Naomi E Allen,Ruth C Travis,Andrew W Roddam,Mazda Jenab,Lars Egevad,Anne Tjønneland,Nina F Johnsen,Kim Overvad,Jakob Linseisen,Sabine Rohrmann,Heiner Boeing,Tobias Pischon,Theodora Psaltopoulou,Antonia Trichopoulou,Dimitrios Trichopoulos,Domenico Palli,Paolo Vineis,Rosario Tumino,Franco Berrino,Lambertus Kiemeney,H Bas Bueno-de-Mesquita,J Ramón Quirós,Carlos A González,Carmen Martinez,Nerea Larrañaga,María Dolores Chirlaque,Eva Ardanaz,Pär Stattin,Göran Hallmans,Kay-Tee Khaw,Sheila Bingham,Nadia Slimani,Pietro Ferrari,Sabina Rinaldi,Elio Riboli.  (2007-09-08)  Plasma carotenoids, retinol, and tocopherols and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition study..  The American journal of clinical nutrition,  86  ((3)): (672-681).  [PMID:17823432]
9. Arun Sreekumar,Laila M Poisson,Thekkelnaycke M Rajendiran,Amjad P Khan,Qi Cao,Jindan Yu,Bharathi Laxman,Rohit Mehra,Robert J Lonigro,Yong Li,Mukesh K Nyati,Aarif Ahsan,Shanker Kalyana-Sundaram,Bo Han,Xuhong Cao,Jaeman Byun,Gilbert S Omenn,Debashis Ghosh,Subramaniam Pennathur,Danny C Alexander,Alvin Berger,Jeffrey R Shuster,John T Wei,Sooryanarayana Varambally,Christopher Beecher,Arul M Chinnaiyan.  (2009-02-13)  Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression..  Nature,  457  ((7231)): (910-914).  [PMID:19212411]
10. Wolfram Gronwald,Matthias S Klein,Raoul Zeltner,Bernd-Detlef Schulze,Stephan W Reinhold,Markus Deutschmann,Ann-Kathrin Immervoll,Carsten A Böger,Bernhard Banas,Kai-Uwe Eckardt,Peter J Oefner.  (2011-03-11)  Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine..  Kidney international,  79  ((11)): (1244-1253).  [PMID:21389975]
11. Dayun Zhao,Jingfu Jia,Xuelei Yu,Xiangjun Sun.  (2011-08-27)  Preparation and characterization of a molecularly imprinted polymer by grafting on silica supports: a selective sorbent for patulin toxin..  Analytical and bioanalytical chemistry,  401  ((7)): (2259-2273).  [PMID:21870071]
12. Yao Yang,Sheng Yuan,Yijun Dai,Guangdong Shang.  (2008-03-15)  [Microplate for high throughput screening of 6-hydroxynicotinic acid transforming strains]..  Wei sheng wu xue bao = Acta microbiologica Sinica,  48  ((1)): (112-115).  [PMID:18338586]
13. Cai-Ming Liu,Ming Xiong,De-Qing Zhang,Miao Du,Dao-Ben Zhu.  (2010-05-08)  Two- and three-dimensional lanthanide-organic frameworks constructed using 1-hydro-6-oxopyridine-3-carboxylate and oxalate ligands..  Dalton transactions (Cambridge, England : 2003),  (29)  ((29)): (5666-5672).  [PMID:20449079]
14. José Ignacio Jiménez,Javier F Juárez,José Luis García,Eduardo Díaz.  (2011-04-01)  A finely tuned regulatory circuit of the nicotinic acid degradation pathway in Pseudomonas putida..  Environmental microbiology,  13  ((7)): (1718-1732).  [PMID:21450002]
15. Zhi Chen, Zhaohe Dong, Xin Ju, Lishi Yan, Liangzhi Li, Donzhi Wei.  (2023)  Screening of a novel and thermostable nicotinate dehydrogenase-producing strain Bacillus paramycoides for efficient synthesis of 6-hydroxynicotinic acid.  BIOCATALYSIS AND BIOTRANSFORMATION,      [PMID:22383884] [10.1080/10242422.2023.2289338]
16. Yu-Ting Shang, Jiufu Qin, Jin-Song Gong, Zi-Kai Wang, Heng Li, Hui Li, Jin-Song Shi, Zheng-Hong Xu.  (2021)  High-throughput screening of a nicotinate dehydrogenase producing Pseudomonas putida mutant for efficient biosynthesis of 6-hydroxynicotinic acid.  Molecular Catalysis,  509  (111600).  [PMID:] [10.1016/j.mcat.2021.111600]
17. Hu Xiaopeng, Xia Yide, Liu Yiwei, Zhao Faqiong, Zeng Baizhao.  (2021)  Determination of patulin using dual-dummy templates imprinted electrochemical sensor with PtPd decorated N-doped porous carbon for amplification.  MICROCHIMICA ACTA,  188  (5): (1-9).  [PMID:33797604] [10.1007/s00604-021-04812-2]
18. Hu Chunhui, Zhao Shuxue, Li Kuiran, Yu Hao.  (2019)  Microbial Degradation of Nicotinamide by a Strain Alcaligenes sp. P156.  Scientific Reports,  (1): (1-11).  [PMID:30842479] [10.1038/s41598-019-40199-0]
19. Wengang Zhang, Yong Han, Xiumei Chen, Xueli Luo, Jianlong Wang, Tianli Yue, Zhonghong Li.  (2017)  Surface molecularly imprinted polymer capped Mn-doped ZnS quantum dots as a phosphorescent nanosensor for detecting patulin in apple juice.  FOOD CHEMISTRY,  232  (145).  [PMID:28490057] [10.1016/j.foodchem.2017.03.156]

Solution Calculators