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6-Methylflavone - 98%, high purity , CAS No.29976-75-8, Antagonist of TAS2R39

  • Moligand™
  • ≥98%
Item Number
M157945
Grouped product items
SKUSizeAvailabilityPrice Qty
M157945-250mg
250mg
In stock
$22.90
M157945-1g
1g
In stock
$70.90
M157945-5g
5g
In stock
$241.90
View related series
TAS2R39 Antagonist

Basic Description

Synonyms6-Methylflavone|29976-75-8|6-methyl-2-phenylchromen-4-one|6-methyl-2-phenyl-4H-chromen-4-one|6-Methyl-2-phenyl-chromen-4-one|K3JCS9D3KJ|6-Methyl-2-phenyl-4H-1-benzopyran-4-one|4H-1-Benzopyran-4-one, 6-methyl-2-phenyl-|UNII-K3JCS9D3KJ|ST069348|Maybridge3_0
Specifications & PurityMoligand™, ≥98%
Biochemical and Physiological Mechanisms6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir
Storage TempStore at 2-8°C
Shipped InWet ice
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of TAS2R39

Associated Targets

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

NR3C1 Tclin Glucocorticoid receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

RORC Tchem Nuclear receptor ROR-gamma 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TNKS Tchem Tankyrase-1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TAS2R39 Tchem Taste receptor type 2 member 39 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AHR Tclin Aryl hydrocarbon receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

AR Tclin Androgen receptor 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALDH1A1 Tchem Retinal dehydrogenase 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

MAPT Tclin Microtubule-associated protein tau 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

TP53 Tchem Cellular tumor antigen p53 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

KDM4E Tchem Lysine-specific demethylase 4E 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 6-methyl-2-phenylchromen-4-one
INCHI InChI=1S/C16H12O2/c1-11-7-8-15-13(9-11)14(17)10-16(18-15)12-5-3-2-4-6-12/h2-10H,1H3
InChi Key NOQJBXPAMJLUSS-UHFFFAOYSA-N
Canonical SMILES CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
Isomeric SMILES CC1=CC2=C(C=C1)OC(=CC2=O)C3=CC=CC=C3
PubChem CID 689013
Molecular Weight 236.27
Reaxy-Rn 179812

Certificates

Certificate of Analysis(COA)

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To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

6 results found

Lot NumberCertificate TypeDateItem
H23031107Certificate of AnalysisJul 14, 2023 M157945
H23031108Certificate of AnalysisJul 14, 2023 M157945
H23031115Certificate of AnalysisJul 14, 2023 M157945
H23031123Certificate of AnalysisJul 14, 2023 M157945
H23031124Certificate of AnalysisJul 14, 2023 M157945
H23031137Certificate of AnalysisJul 14, 2023 M157945

Chemical and Physical Properties

SolubilitySoluble in Methanol
Boil Point(°C)235°C/12mmHg(lit.)
Melt Point(°C)121 °C

Safety and Hazards(GHS)

Reaxy-Rn 179812

Related Documents

Solution Calculators