7-Amino-4-methyl-3-coumarinylacetic acid(AMCA) - suitable for fluorescence,90% (HPLC), high purity , CAS No.106562-32-7

Item Number
A131039
Grouped product items
SKUSizeAvailabilityPrice Qty
A131039-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$45.90
A131039-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$74.90
A131039-250mg
250mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$149.90
A131039-500mg
500mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90

Basic Description

Synonyms106562-32-7 | 2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid | 7-Amino-4-methylcoumarin-3-acetic acid | 7-Amino-4-methyl-3-coumarinylacetic acid | AMCA acid | 2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid | AMCA-H | 2H-1-Benzopyran-3-acetic acid, 7-amino-4-m
Specifications & Puritysuitable for fluorescence,90% (HPLC)
Shipped InNormal
Gradefor fluorescence analysis
Product Description

Non-activated, Amine-reactive, fluorescent probe that can be conjugated to biomolecules.
A blue fluorophore useful for immunofluorescence and peptide labeling.AMCA is a useful agent for labeling proteins. Demonstrates a characteristic absorption peak at 345 nm with a fluorescence emission at 440-460 nm (blue region); however, when conjugated with proteins the absorption peak shifts to 355 nm with a fluorescence emission at 440-460 nm. It has a high fluorescence yield with a sufficient Stokes shift (100 nm) and is relatively photostable.Relatively easy to activate and couple to the N-terminal amino group of a peptide resulting in an acid stable amide bond.

Fluorescence: λex 350 nm,λem 433 nm in methanol

Names and Identifiers

IUPAC Name 2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid
INCHI InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)
InChi Key QEQDLKUMPUDNPG-UHFFFAOYSA-N
Canonical SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)O
Isomeric SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)O
WGK Germany 3
PubChem CID 129367
Molecular Weight 233.22
Beilstein 7927205

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

10 results found

Lot NumberCertificate TypeDateItem
G2214077Certificate of AnalysisApr 07, 2024 A131039
G2214078Certificate of AnalysisApr 07, 2024 A131039
L2327081Certificate of AnalysisDec 18, 2023 A131039
L2327082Certificate of AnalysisDec 18, 2023 A131039
L2327083Certificate of AnalysisDec 18, 2023 A131039
K2111397Certificate of AnalysisAug 16, 2023 A131039
K2111398Certificate of AnalysisAug 16, 2023 A131039
K2111399Certificate of AnalysisAug 16, 2023 A131039
K2111554Certificate of AnalysisAug 16, 2023 A131039
G2214079Certificate of AnalysisJun 11, 2022 A131039

Chemical and Physical Properties

SolubilitySoluble in DMF, DMSO, aqueous base, 10% NaOH solution (freely soluble) at 20 °C, alcohol at 20 °C, acetone at 20 °C, and ether (slightly soluble) at 20 °C. Insoluble in water.
SensitivityLight & Moisture Sensitive

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

WGK Germany 3

Related Documents

Citations of This Product

1. Ti Qin, Pinhao Li, Jun Li, Qianqian Guo, Ying Chen, Yu-E Wang, Ling Tao, Jian Huang, Xiangchun Shen, Xingjie Wu.  (2023)  Size-Exclusion Chromatography-Based Extracellular Vesicles Size Subtyping and Multiplex Membrane Protein Profiling for Differentiating Gastrointestinal Cancer Prognosis.  ANALYST,      [PMID:37842723]

References

1. Ti Qin, Pinhao Li, Jun Li, Qianqian Guo, Ying Chen, Yu-E Wang, Ling Tao, Jian Huang, Xiangchun Shen, Xingjie Wu.  (2023)  Size-Exclusion Chromatography-Based Extracellular Vesicles Size Subtyping and Multiplex Membrane Protein Profiling for Differentiating Gastrointestinal Cancer Prognosis.  ANALYST,      [PMID:37842723]

Solution Calculators