Click Here for 5% Off Your First Aladdin Purchase!

7-chloro-3-oxo-8-(1,3-thiazol-5-ylmethylamino)-11,16-dioxa-2,4,19,21-tetrazatricyclo[15.3.1.05,10]henicosa-1(20),5,7,9,17(21),18-hexaene-18-carbonitrile , CAS No.C608993, Inhibitor of checkpoint kinase 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of muscle associated receptor tyrosine kinase;Inhibitor of nemo like kinase;Inhibitor of NIMA related kinase 11;Inhibitor of NIMA related kinase 3;Inhibitor of

  • Moligand™
Item Number
C608993
Grouped product items
SKUSizeAvailabilityPrice Qty
C608993-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
C608993-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,000.90

Basic Description

Synonymscompound 25
Specifications & PurityMoligand™
GradeMoligand™
Action TypeINHIBITOR
Mechanism of actionInhibitor of checkpoint kinase 1;Inhibitor of fms related receptor tyrosine kinase 1;Inhibitor of muscle associated receptor tyrosine kinase;Inhibitor of nemo like kinase;Inhibitor of NIMA related kinase 11;Inhibitor of NIMA related kinase 3;Inhibitor of

Names and Identifiers

INCHI InChI=1S/C20H18ClN7O3S/c21-13-5-15-17(6-14(13)24-9-12-8-23-11-32-12)30-3-1-2-4-31-19-16(7-22)25-10-18(27-19)28-20(29)26-15/h5-6,8,10-11,24H,1-4,9H2,(H2,26,27,28,29)
InChi Key AZTMYWWWILJAKW-UHFFFAOYSA-N
Canonical SMILES N#Cc1ncc2nc1OCCCCOc1c(NC(=O)N2)cc(Cl)c(c1)NCc1cncs1
Isomeric SMILES C1CCOC2=NC(=CN=C2C#N)NC(=O)NC3=CC(=C(C=C3OC1)NCC4=CN=CS4)Cl
PubChem CID 44444843

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Tao ZF, Chen Z, Bui MH, Kovar P, Johnson E, Bouska J, Zhang H, Rosenberg S, Sowin T, Lin NH.  (2007)  Macrocyclic ureas as potent and selective Chk1 inhibitors: an improved synthesis, kinome profiling, structure-activity relationships, and preliminary pharmacokinetics..  Bioorg Med Chem Lett,  17  (23): (6593-601).  [PMID:17935989]

Solution Calculators