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7-HC-γ-linolenate - ≥98%, high purity , CAS No.161180-12-7
a useful PLA2 fluorogenic substrate for an assay applications with purified enzymes
Basic Description Synonyms HY-D1647 | (2-oxochromen-7-yl) (6Z,9Z,12Z)-octadeca-6,9,12-trienoate | LPIXSKJJCANUQD-QNEBEIHSSA-N | 7-hydroxycoumarinyl- | 2-Oxo-2H-chromen-7-yl (6Z,9Z,12Z)-octadeca-6,9,12-trienoate | AKOS040756080 | CHEBI:183481 | PD021358 | 7-hydroxycoumarinyl-gamma-l Specifications & Purity ≥98% Storage Temp Store at -80°C Shipped In Ice chest + Ice pads Product Description 7-HC-γ-linolenate is a PLA2 fluorogenic substrate for use in assays with phospholipid and Ca|2+|. 7-HC-γ-linolenate is for use with purified enzyme, as this substrate is nonspecific (1,2). Ideal for drug discovery, HTS, and similar applications. drug discovery, HTS, and similar applications. 7-HC-γ-linolenate is a substrate of cPLA2. Ex.: 360 nm, Em.: 460 nm
Product Properties Excitation and Emision Ranges λex 360 nm,λem 460 nm;λex 335 nm,λem 450 nm
Names and Identifiers IUPAC Name (2-oxochromen-7-yl) (6Z,9Z,12Z)-octadeca-6,9,12-trienoate INCHI InChI=1S/C27H34O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(28)30-24-20-18-23-19-21-27(29)31-25(23)22-24/h6-7,9-10,12-13,18-22H,2-5,8,11,14-17H2,1H3/b7-6-,10-9-,13-12- InChi Key LPIXSKJJCANUQD-QNEBEIHSSA-N Canonical SMILES CCCCCC=CCC=CCC=CCCCCC(=O)OC1=CC2=C(C=C1)C=CC(=O)O2 Isomeric SMILES CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)OC1=CC2=C(C=C1)C=CC(=O)O2 PubChem CID 91746434 Molecular Weight 422.56
Chemical and Physical Properties Solubility Soluble in DMSO (50 mg/ml), 100% ethanol (35 mg/ml), and DMF (50 mg/ml).
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