| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| M115185-20mg | 20mg | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $69.90 |
Potent, selective CYP2A6 inhibitor
| Synonyms | methoxsalen|8-Methoxypsoralen|298-81-7|XANTHOTOXIN|Meladinine|Oxypsoralen|9-Methoxy-7H-furo[3,2-g]chromen-7-one|8-MOP|Oxsoralen|Xanthotoxine|Ammoidin|Puvalen|Meladinin|Meloxine|Uvadex|Meladoxen|Ammodin|8-Methoxypsoralene|Methoxa-Dome|New-Meladinin|Zanthot |
|---|---|
| Specifications & Purity | Moligand™, analytical standard, ≥98% |
| Biochemical and Physiological Mechanisms | 8-Methoxypsoralen is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrom |
| Shipped In | Normal |
| Grade | analytical standard, Moligand™ |
| Action Type | AGONIST |
| Mechanism of action | Agonist of TAS2R20 |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description | A potent suicide inhibitor of cytochrome P-450. |
| ALogP | 1.9 |
|---|
| IUPAC Name | 9-methoxyfuro[3,2-g]chromen-7-one |
|---|---|
| INCHI | InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3 |
| InChi Key | QXKHYNVANLEOEG-UHFFFAOYSA-N |
| Canonical SMILES | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 |
| Isomeric SMILES | COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2 |
| WGK Germany | 3 |
| RTECS | LV1400000 |
| Alternate CAS | 298-81-7 |
| PubChem CID | 4114 |
| NSC Number | 45923 |
| UN Number | 1759 |
| Packing Group | I |
| MeSH Entry Terms | 8 Methoxypsoralen;8 MOP;8-Methoxypsoralen;8-MOP;8MOP;Ammoidin;Deltasoralen;Dermox;Geroxalen;M\u00e9ladinine;Meladinina;Meladinine;Meloxine;Methoxa Dome;Methoxa-Dome;Methoxsalen;Oxsoralen;Oxsoralen Ultra;Oxsoralen-Ultra;Puvalen;Ultramop;Xanthotoxin |
| Molecular Weight | 216.19 |
| Beilstein | 196453 |
| Reaxy-Rn | 196453 |
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| Solubility | Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water. |
|---|---|
| Melt Point(°C) | 145℃-150℃ |
| Pictogram(s) | GHS07 |
|---|---|
| Signal | Warning |
| Hazard Statements | H302:Harmful if swallowed H317:May cause an allergic skin reaction |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P270:Do not eat, drink or smoke when using this product. P272:Contaminated work clothing should not be allowed out of the workplace. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. |
| WGK Germany | 3 |
| RTECS | LV1400000 |
| Reaxy-Rn | 196453 |
| Class | 8 |
| Merck Index | 5988 |
I2301179