Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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A288088-1mg | 1mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $59.90 | |
A288088-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $164.90 | |
A288088-10mg | 10mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $263.90 | |
A288088-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $527.90 | |
A288088-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $843.90 | |
A288088-100mg | 100mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,349.90 |
Potent TRPV1 antagonist
Synonyms | 581809-67-8|A-425619|1-(4-(trifluoromethyl)benzyl)-3-(isoquinolin-5-yl)urea|1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea|1-isoquinolin-5-yl-3-[[4-(trifluoromethyl)phenyl]methyl]urea|A 425619|N2NOA4CE04|CHEMBL104028|A425619|1-Isoquinolin-5-yl-3-(4- |
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Specifications & Purity | 95% |
Storage Temp | Store at -20°C |
Shipped In | Ice chest + Ice pads |
Action Type | CHANNEL BLOCKER |
Mechanism of action | Channel blocker of TRPV1 |
Product Description |
A-425619, a potent and selective TRPV1 receptor antagonist, is effective in alleviating acute and chronic inflammatory pain and postoperative pain.
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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IUPAC Name | 1-isoquinolin-5-yl-3-[[4-(trifluoromethyl)phenyl]methyl]urea |
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INCHI | InChI=1S/C18H14F3N3O/c19-18(20,21)14-6-4-12(5-7-14)10-23-17(25)24-16-3-1-2-13-11-22-9-8-15(13)16/h1-9,11H,10H2,(H2,23,24,25) |
InChi Key | SJGVXVZUSQLLJB-UHFFFAOYSA-N |
Canonical SMILES | C1=CC2=C(C=CN=C2)C(=C1)NC(=O)NCC3=CC=C(C=C3)C(F)(F)F |
Isomeric SMILES | C1=CC2=C(C=CN=C2)C(=C1)NC(=O)NCC3=CC=C(C=C3)C(F)(F)F |
PubChem CID | 8068410 |
Molecular Weight | 345.32 |
PubChem CID | 8068410 |
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CAS Registry No. | 581809-67-8 |
ChEMBL Ligand | CHEMBL104028 |
Enter Lot Number to search for COA:
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Lot Number | Certificate Type | Date | Item |
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E2422402 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422442 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422447 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422462 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422464 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422465 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422477 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422481 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422509 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422511 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422512 | Certificate of Analysis | Feb 26, 2024 | A288088 |
E2422523 | Certificate of Analysis | Feb 26, 2024 | A288088 |
Solubility | Solvent:DMSO, Max Conc. mg/mL: 34.53, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 34.53, Max Conc. mM: 100 |
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