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α5IA - 97%, high purity , CAS No.215874-86-5, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit

  • Moligand™
  • ≥97%
Item Number
I346768
Grouped product items
SKUSizeAvailabilityPrice Qty
I346768-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
I346768-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$121.90
I346768-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$182.90
I346768-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
I346768-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$461.90
I346768-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$661.90

Basic Description

SynonymsAM85665|J-014159|L-822179|UNII-1M7NI1A92L|.ALPHA. 5IA|3-(5-Methyl-1,2-oxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine|A14343|CS-0066094|5-methyl-3-[6-[(1-methyltriazol-4-yl)methoxy]-[1,2,4]triazolo[3,4-a]phthalazi
Specifications & PurityMoligand™, ≥97%
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeALLOSTERIC MODULATOR
Mechanism of actionAllosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α5 subunit
Product Description

α5IA (L-822179) is a selective α5 GABAA receptor inverse agonist with neuroprotective potential.

Associated Targets

GABRA1 Tclin Gamma-aminobutyric acid receptor subunit alpha-1 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRG2 Tclin Gamma-aminobutyric acid receptor subunit gamma-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA3 Tclin Gamma-aminobutyric acid receptor subunit alpha-3 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA5 Tclin Gamma-aminobutyric acid receptor subunit alpha-5 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GABRA2 Tclin Gamma-aminobutyric acid receptor subunit alpha-2 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 5-methyl-3-[6-[(1-methyltriazol-4-yl)methoxy]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl]-1,2-oxazole
INCHI InChI=1S/C17H14N8O2/c1-10-7-14(22-27-10)16-20-19-15-12-5-3-4-6-13(12)17(21-25(15)16)26-9-11-8-24(2)23-18-11/h3-8H,9H2,1-2H3
InChi Key NZMJFRXKGUCYNP-UHFFFAOYSA-N
Canonical SMILES CC1=CC(=NO1)C2=NN=C3N2N=C(C4=CC=CC=C43)OCC5=CN(N=N5)C
Isomeric SMILES CC1=CC(=NO1)C2=NN=C3N2N=C(C4=CC=CC=C43)OCC5=CN(N=N5)C
Alternate CAS 215874-86-5
PubChem CID 6918451
MeSH Entry Terms 3-(5-methylisoxazol-3-yl)-6-((1-methyl-1,2,3-triazol-4-yl)methyloxy)-1,2,4-triazolo(3,4-a)phthalazine;alpha5IA cpd
Molecular Weight 362.35

Certificates

Certificate of Analysis(COA)

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12 results found

Lot NumberCertificate TypeDateItem
G2419102Certificate of AnalysisApr 08, 2024 I346768
G2419103Certificate of AnalysisApr 08, 2024 I346768
G2419112Certificate of AnalysisApr 08, 2024 I346768
G2419121Certificate of AnalysisApr 08, 2024 I346768
G2419122Certificate of AnalysisApr 08, 2024 I346768
G2419123Certificate of AnalysisApr 08, 2024 I346768
G2419124Certificate of AnalysisApr 08, 2024 I346768
G2419125Certificate of AnalysisApr 08, 2024 I346768
G2419126Certificate of AnalysisApr 08, 2024 I346768
G2419127Certificate of AnalysisApr 08, 2024 I346768
G2419128Certificate of AnalysisApr 08, 2024 I346768
G2419129Certificate of AnalysisApr 08, 2024 I346768

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Chemical and Physical Properties

SolubilitySoluble in DMSO: >2 mg/mL
Sensitivitylight sensitive

Related Documents

Solution Calculators