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Abarelix Acetate, CAS No.547741-72-0, Antagonist of GnRH 1 receptor

  • Moligand™
  • ≥98%
Features and benefits
    Item Number
    A338920
    Grouped product items
    SKUSizeAvailabilityPrice Qty
    A338920-5mg
    5mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $74.90
    A338920-10mg
    10mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $145.90
    A338920-25mg
    25mg
    Available within 8-12 weeks(?)
    Production requires sourcing of materials. We appreciate your patience and understanding.
    $289.90

    a synthetic peptide antagonist to GnRH receptors

    View related series
    GnRH1 receptor Antagonist

    Basic Description

    Product NameAbarelix Acetate, CAS No.547741-72-0
    SynonymsMS-32159 | L02XB01 | Plenaxis depot | BDBM50102442 | Plenaxis (TN) | PPI 149R3827 | W486SJ5824 | PPI 149 | PPI149 | PPI-149 | HY-13534 | l-1,4-Dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide | AKOS040733331 | N-acetyl-3
    GradeMoligand™
    Product Description

    Abarelix acetate is a synthetic peptide gonadotropin releasing hormone receptor (GnRH) antagonist

    Specifications & Purity98%
    SequenceAc-D-2-Nal-D-4-Cl-Phe-D-3-Pal-Ser-N-Me-Tyr-D-Asn-Leu-Lys(ipr)-Pro-D-Ala-NH2
    Action TypeANTAGONIST
    Mechanism of actionAntagonist of GnRH 1 receptor

    Associated Targets

    GNRHR Tclin Gonadotropin-releasing hormone receptor 0 Activities

    Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

    Product Specifications

    Storage TempStore at -20°C
    Shipped InIce chest + Ice pads
    CAS547741-72-0

    Certificates

    Certificate of Analysis(COA)

    Enter Lot Number to search for COA:

    To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

    3 results found

    Lot NumberCertificate TypeDateItem
    C2425131Certificate of AnalysisMar 06, 2024 A338920
    C2425132Certificate of AnalysisMar 06, 2024 A338920
    C2425133Certificate of AnalysisMar 06, 2024 A338920

    Genetic information

    Alternate NamesMS-32159 | L02XB01 | Plenaxis depot | BDBM50102442 | Plenaxis (TN) | PPI 149R3827 | W486SJ5824 | PPI 149 | PPI149 | PPI-149 | HY-13534 | l-1,4-Dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine hydrobromide | AKOS040733331 | N-acetyl-3
    Reference
    • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
    • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
    • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
    • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
    • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
    • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
    • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
    • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
    • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
    • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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