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ABI-H0731 - 99%, high purity , Core antigen inhibitor, CAS No.2090064-66-5, Core antigen inhibitor

  • ≥99%
Item Number
A579444
Grouped product items
SKUSizeAvailabilityPrice Qty
A579444-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
A579444-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$197.90
A579444-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$315.90
A579444-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$642.90
A579444-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$989.90
View related series
Anti-infection HBV

Basic Description

Synonyms11-oxo-N-((2-(trifluoromethyl)thiazol-5-yl)methyl)-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide-5,5-dioxide
Specifications & Purity99%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Action TypeINHIBITOR
Mechanism of actionCore antigen inhibitor
Product Description

Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor. Vebicorvir (ABI-H0731) suppresses covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM。

Product Properties

ALogP2.4

Names and Identifiers

IUPAC Name 6,11,11-trioxo-N-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-5H-benzo[b][1,4]benzothiazepine-3-carboxamide
INCHI InChI=1S/C19H12F3N3O4S2/c20-19(21,22)18-24-9-11(30-18)8-23-16(26)10-5-6-15-13(7-10)25-17(27)12-3-1-2-4-14(12)31(15,28)29/h1-7,9H,8H2,(H,23,26)(H,25,27)
InChi Key LBJVBJYMZKEREY-UHFFFAOYSA-N
Canonical SMILES C1=CC=C2C(=C1)C(=O)NC3=C(S2(=O)=O)C=CC(=C3)C(=O)NCC4=CN=C(S4)C(F)(F)F
Isomeric SMILES C1=CC=C2C(=C1)C(=O)NC3=C(S2(=O)=O)C=CC(=C3)C(=O)NCC4=CN=C(S4)C(F)(F)F
PubChem CID 139394142
Molecular Weight 467.44

Certificates

Certificate of Analysis(COA)

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11 results found

Lot NumberCertificate TypeDateItem
B2426798Certificate of AnalysisJan 19, 2024 A579444
B2426807Certificate of AnalysisJan 19, 2024 A579444
B2426808Certificate of AnalysisJan 19, 2024 A579444
B2426809Certificate of AnalysisJan 19, 2024 A579444
B2426813Certificate of AnalysisJan 19, 2024 A579444
B2426814Certificate of AnalysisJan 19, 2024 A579444
B2426815Certificate of AnalysisJan 19, 2024 A579444
B2426816Certificate of AnalysisJan 19, 2024 A579444
B2426817Certificate of AnalysisJan 19, 2024 A579444
B2426824Certificate of AnalysisJan 19, 2024 A579444
B2426825Certificate of AnalysisJan 19, 2024 A579444

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Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H302:Harmful if swallowed

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

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