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Abn-CBD - ≥98%, high purity , CAS No.22972-55-0, Agonist of GPR18;Agonist of GPR55

  • Moligand™
  • ≥98%
Item Number
C275258
Grouped product items
SKUSizeAvailabilityPrice Qty
C275258-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$46.90
C275258-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$177.90
C275258-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$273.90
C275258-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$615.90
C275258-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$989.90
C275258-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,499.90
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Non-CB 1 /CB 2 endocannabinoid receptor ligand

View related series
GPR18 Agonist GPR55 Agonist

Basic Description

SynonymsAbnormal cannabidiol|Abn-cbd|22972-55-0|Abnormal-cannabidiol|CAY10429|T4WF2D7YPH|4-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol|CHEMBL499876|Resorcinol, 4-p-mentha-1,8-dien-3-yl-5-pentyl-, (-)-(E)-|1,3-Benzenediol, 4-[(1R
Specifications & Purity≥98%
Storage TempProtected from light,Store at -20°C,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeAGONIST
Mechanism of actionAgonist of GPR18;Agonist of GPR55
Product Description

Abn-CBD is a neurobehaviorally inactive cannabinoid that acts as a selective agonist for GPR55 (EC50 values are 2.5, >30 and >30 μM at GPR55, CB1 and CB2 receptors respectively). Increases phosphorylation of protein kinases in, and migration of, human umbilical vein endothelial cells.

Associated Targets

GPR18 Tchem N-arachidonyl glycine receptor 1 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GPR55 Tclin G-protein coupled receptor 55 2 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name 4-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
INCHI InChI=1S/C21H30O2/c1-5-6-7-8-16-12-17(22)13-20(23)21(16)19-11-15(4)9-10-18(19)14(2)3/h11-13,18-19,22-23H,2,5-10H2,1,3-4H3/t18-,19+/m0/s1
InChi Key YWEZXUNAYVCODW-RBUKOAKNSA-N
Canonical SMILES CCCCCC1=C(C(=CC(=C1)O)O)C2C=C(CCC2C(=C)C)C
Isomeric SMILES CCCCCC1=C(C(=CC(=C1)O)O)[C@@H]2C=C(CC[C@H]2C(=C)C)C
PubChem CID 89949
Molecular Weight 314.46

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in methyl acetate；ethanol (~35 mg/ml)；DMSO (~35 mg/ml)；DMF (~35 mg/ml)；DMSO:PBS (1:3, pH 7.2) (0.25 mg/ml).
SensitivityLight sensitive；Moisture sensitive

Related Documents

 SDS

 Specification Sheet

References

1. Járai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E et al..  (1999)  Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors..  Proc Natl Acad Sci USA,  96  (24): (14136-41).  [PMID:10570211]

Solution Calculators

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