Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Basic Description
| Synonyms | acetylenedicarboxylic acid|142-45-0|2-butynedioic acid|but-2-ynedioic acid|Butynedioic acid|acetylenedicarboxylate|acetylene dicarboxylic acid|2-Butyne-1,4-dioic acid|2D2OJ4KO44|CHEBI:30781|NSC-1903|NSC631597|NSC-631597|NSC 631597|Acetylenedicarboxylicaci |
|---|---|
| Specifications & Purity | ≥95% |
| Storage Temp | Store at 2-8°C,Argon charged |
| Shipped In | Wet ice |
| Product Description | Acetylenedicarboxylic acid is employed in the preparation of dimethyl acetylenedicarboxylate and potassium hydrogenacetylenedicarboxylate. It is also used as a laboratory reagent. Further, it is used as a precursor in organic synthesis and also serves as a pharmaceutical intermediate. |
Associated Targets
SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities
Names and Identifiers
Certificates
Certificate of Analysis(COA)
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 L2320237 | Certificate of Analysis | Dec 04, 2023 | A113362 |
| L2320238 | Certificate of Analysis | Dec 04, 2023 | A113362 |
| L2320239 | Certificate of Analysis | Dec 04, 2023 | A113362 |
| I2315140 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| I2315141 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| I2315142 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| I2315143 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| I2315144 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| I2315145 | Certificate of Analysis | Aug 31, 2023 | A113362 |
| J2009551 | Certificate of Analysis | Aug 09, 2022 | A113362 |
| J2218305 | Certificate of Analysis | Aug 12, 2021 | A113362 |
| J2218496 | Certificate of Analysis | Aug 12, 2021 | A113362 |
| J2218499 | Certificate of Analysis | Aug 12, 2021 | A113362 |
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Chemical and Physical Properties
| Solubility | Soluble in diethyl ether and water. |
|---|---|
| Sensitivity | Heat and Air sensitive |
| Flash Point(°F) | 131℃ |
| Flash Point(°C) | 131℃ |
| Melt Point(°C) | 180-187°C |
Safety and Hazards(GHS)
| Pictogram(s) | GHS06, GHS05, GHS07 |
|---|---|
| Signal | Danger |
| Hazard Statements | H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H301:Toxic if swallowed H314:Causes severe skin burns and eye damage |
| Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P405:Store locked up. P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P260:Do not breathe dust/fume/gas/mist/vapors/spray. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P363:Wash contaminated clothing before reuse. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes. P301+P316:IF SWALLOWED: Get emergency medical help immediately. P305+P354+P338:IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P337+P317:If eye irritation persists: Get medical help. P332+P317:If skin irritation occurs: Get medical help. P302+P361+P354:IF ON SKIN: Take off Immediately all contaminated clothing. Immediately rinse with water for several minutes. P316:Get emergency medical help immediately. P319:Get medical help if you feel unwell. |
| WGK Germany | 3 |
| Reaxy-Rn | 878357 |
Related Documents
Alternative Products
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Dimethyl acetylenedicarboxylateStarting at $13.90
References
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| 2. Issa Yavari,Hasan Zare,Bita Mohtat. (2006-06-14) Three-component synthesis of dialkyl 2-(alkylimino-methylene)3- (2,2,5-trimethyl-4,6-dioxo-1,3-dioxan-5-yl)-succinates.. Molecular diversity, 10 ((2)): (247-250). [PMID:16770515] |
| 3. Issa Yavari,Mehdi Sirouspour,Sanaz Souri. (2006-06-17) Three-component synthesis of functionalized 5-oxo-4,5-dihydroindeno[1,2-b]pyrans.. Molecular diversity, 10 ((2)): (265-270). [PMID:16779612] |
| 4. Kyungho Park,Goun Bae,Jeongju Moon,Jaehoon Choe,Kwang Ho Song,Sunwoo Lee. (2010-08-28) Synthesis of symmetrical and unsymmetrical diarylalkynes from propiolic acid using palladium-catalyzed decarboxylative coupling.. The Journal of organic chemistry, 75 ((18)): (6244-6251). [PMID:20795634] |
| 5. Poovan Shanmugavelan,Sangaraiah Nagarajan,Murugan Sathishkumar,Alagusundaram Ponnuswamy,Perumal Yogeeswari,Dharmarajan Sriram. (2011-11-09) Efficient synthesis and in vitro antitubercular activity of 1,2,3-triazoles as inhibitors of Mycobacterium tuberculosis.. Bioorganic & medicinal chemistry letters, 21 ((24)): (7273-7276). [PMID:22061642] |
| 6. Abbas Ali Esmaeili,Mahdieh Zangouei,Rahele Hosseinabadi,Ali Reza Fakhari. (2011-12-17) Three-component reactions of isocyanides, dialkyl acetylenedicarboxylates, and trans-cinnamoyl chlorides for the synthesis of highly functionalized 2-vinyl furans.. Molecular diversity, 16 ((1)): (145-150). [PMID:22173695] |
| 7. Saeed Balalaie,Morteza Ashouriha,Frank Rominger,Hamid Reza Bijanzadeh. (2013-01-24) An efficient and facile synthesis of 3-amino-5-chromenyl-butenolides from 3-formyl chromone, dialkyl acetylenedicarboxylate, and primary amines.. Molecular diversity, 17 ((1)): (55-61). [PMID:23341007] |
| 8. A S Subbaraman,Z A Kazi,A S Choughuley,M S Chadha. (1980-12-01) Urea-acetylene dicarboxylic acid reaction: a likely pathway for prebiotic uracil formation.. Origins of life, 10 ((4)): (343-347). [PMID:7454254] |
| 9. Heiner Eckert. (2012-01-24) Diversity oriented syntheses of conventional heterocycles by smart multi component reactions (MCRs) of the last decade.. Molecules (Basel, Switzerland), 17 ((1)): (1074-1102). [PMID:22267194] |