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Acridine Orange hydrochloride - >99%, high purity , CAS No.65-61-2

1 Citations

≥99%

CAS#: 65-61-2
Formula: C₁₇H₂₀ClN₃
Molecular Weight: 301.81
MDL number: MFCD00012660
PubChem CID: 517204

Item Number

A304298

Grouped product items
SKU	Size	Availability	Price	Qty
A304298-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$121.90
A304298-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$340.90

Nucleic acid binding dye

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Dye

Basic Description

Synonyms	N3,N3,N6,N6-tetramethylacridine-3,6-diamine hydrochloride \| acridine orange hydrochloride \| Acridine Orange (Hydrochloride)
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Cell and organelle membrane permeable nucleic acid binding dye. Emits green fluorescence when bound to double-stranded DNA and red fluorescence when bound to RNA or single-stranded DNA. Used in cell cycle and apoptosis studies and as a lysosomal dye.
Storage Temp	Protected from light,Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads
Product Description	A rigorously purified zinc-free material suitable for use in flow cytometry. Acridine Orange hydrochloride hydrate dye has been used: • to stain intracellular acidic vesicles. • to measure lysosomal membrane permeability (LMP). • or autophagy detection. Fluorescent stain for nucleic acids in agarose and polyacrylamide gels. Has been used to study apoptosis in various cell culture and tissue models.

Names and Identifiers

IUPAC Name	3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine;hydrochloride
INCHI	InChI=1S/C17H19N3.ClH/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;/h5-11H,1-4H3;1H
InChi Key	VSTHNGLPHBTRMB-UHFFFAOYSA-N
Canonical SMILES	CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl
Isomeric SMILES	CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl
PubChem CID	517204
Molecular Weight	301.81

Certificates

Certificate of Analysis(COA)

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5 results found

Lot Number	Certificate Type	Date	Item
G2415813	Certificate of Analysis	Jul 05, 2024	A304298
G2416637	Certificate of Analysis	Jul 05, 2024	A304298
A2425086	Certificate of Analysis	Jun 14, 2022	A304298
G2205051	Certificate of Analysis	Jun 14, 2022	A304298
G2205052	Certificate of Analysis	Jun 14, 2022	A304298

Solubility

Solvent:water, Max Conc. mg/mL: 30.18, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 30.18, Max Conc. mM: 100

Sensitivity

Hygroscopic；light sensitive；heat sensitive

Safety and Hazards(GHS)

Pictogram(s)	GHS08
Signal	Danger
Hazard Statements	H340:May cause genetic defects
Precautionary Statements	P405:Store locked up. P501:Dispose of contents/container to ... P281:Use personal protective equipment as required. P203:Obtain, read and follow all safety instructions before use. P318:if exposed or concerned, get medical advice.

Citations of This Product

1. Hao-kun Hua, Hui-xing Guo, Wen-bin Liu, Zi-shang Liu, Chao-fan He, Wan-ting Du, Yang-yang Huang, Wei Xiong, Li-ren Ding, Guang-zhen Jiang. (2023) Dietary nicotinic acid promotes the growth and tryptophan metabolome of Chinese mitten crab (Eriocheir sinensis) through ACMSD and NADs. Aquaculture Reports, 33 (15): (101800). [PMID:10716937]

References

1. Hao-kun Hua, Hui-xing Guo, Wen-bin Liu, Zi-shang Liu, Chao-fan He, Wan-ting Du, Yang-yang Huang, Wei Xiong, Li-ren Ding, Guang-zhen Jiang. (2023) Dietary nicotinic acid promotes the growth and tryptophan metabolome of Chinese mitten crab (Eriocheir sinensis) through ACMSD and NADs. Aquaculture Reports, 33 (15): (101800). [PMID:10716937]

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