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Adenosine 2′:3′-cyclic monophosphate sodium salt - 97%, high purity , CAS No.37063-35-7
Basic Description Synonyms 2',3'-cAMP sodium salt|37063-35-7|Adenosine-2',3'-cyclic Monophosphate Sodium Salt|Adenosine-2':3'-cyclic monophosphate, sodium salt|sodium;[(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxido-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]metha Specifications & Purity 97% Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Product Description Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.
Names and Identifiers IUPAC Name sodium;[(3aR,4R,6R,6aR)-4-(6-aminopurin-9-yl)-2-oxido-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-6-yl]methanol INCHI InChI=1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1 InChi Key VSDSIACSNXHGOV-MCDZGGTQSA-M Canonical SMILES [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H]4OP([O-])(=O)O[C@@H]34 Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]4[C@@H]([C@H](O3)CO)OP(=O)(O4)[O-])N.[Na+] WGK Germany 3 Alternate CAS 634-01-5 PubChem CID 23666344 Molecular Weight 351.19
Chemical and Physical Properties Solubility It is soluble in DMSO, water. Sensitivity Moisture sensitive Melt Point(°C) 241-243 °C
Safety and Hazards(GHS) Pictogram(s) GHS07 Signal Warning Hazard Statements H332: Harmful if inhaled
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P271: Use only outdoors or in a well-ventilated area.
P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P317: Get emergency medical help.
WGK Germany 3
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