Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate - 99%, high purity , CAS No.37839-81-9

1 Citations
  • ≥99%
Item Number
A122959
Grouped product items
SKUSizeAvailabilityPrice Qty
A122959-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$17.90
A122959-100mg
100mg
In stock
$55.90
A122959-500mg
500mg
In stock
$247.90
A122959-2.5g
2.5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,115.90

Basic Description

SynonymsCamp sodium salt | c-AMP sodium salt | cAMP-Na | AC-32412 | MLS001333136 | (4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, sodium salt | Cyclic AMP Sodium Salt | NCGC00179131-02 | sodium (4a
Specifications & Purity≥99%
Biochemical and Physiological MechanismsNaturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

Adenosine 3′,5′-cyclic monophosphate sodium salt is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is an activator of Epac.
Adenosine-3′,5′-cyclic monophosphate (cAMP) is an activator of cyclic-AMP-dependent protein kinase A (PKA). The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis. Exogneous cAMP plays a role in the spontaneous activity and contraction of the heart muscle.

Associated Targets(Human)

AVPR1B Tclin Vasopressin V1b receptor (1301 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRKAR1A Tbio cAMP-dependent protein kinase type I-alpha regulatory subunit (18 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PRKAR2A Tchem cAMP-dependent protein kinase type II-alpha regulatory subunit (246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXFP1 Tchem Relaxin receptor 1 (6345 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RXFP2 Tbio Relaxin receptor 2 (377 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF4 Tchem Rap guanine nucleotide exchange factor 4 (11476 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hcn2 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (15 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cnga2 Cyclic nucleotide-gated olfactory channel (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cnga2 CNGA2/CNGA4/CNGB1 (5 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

Pubchem Sid488200444
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488200444
IUPAC Name sodium;(4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
INCHI InChI=1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
InChi Key BXJBFCKTIWRKMQ-MCDZGGTQSA-M
Canonical SMILES C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(O1)[O-].[Na+]
Isomeric SMILES C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(O1)[O-].[Na+]
WGK Germany 2
RTECS AU7357900
PubChem CID 23669773
Molecular Weight 351.19(as Anhydrous)
Beilstein 54612
Reaxy-Rn 5215289

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
I1510113Certificate of AnalysisMay 10, 2023 A122959
C2302423Certificate of AnalysisMar 14, 2023 A122959
C2302424Certificate of AnalysisMar 13, 2023 A122959
D1820076Certificate of AnalysisFeb 18, 2022 A122959

Chemical and Physical Properties

SensitivityHeat sensitive

Safety and Hazards(GHS)

WGK Germany 2
RTECS AU7357900
Reaxy-Rn 5215289

Related Documents

Citations of This Product

1. Liling Wang, Huan Wang, Jing Luo, Ting Xie, Gil Mor, Aihua Liao.  (2022)  Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss.  Theranostics,  12  (17): ( 7216–7236).  [PMID:36438479]

References

1. Liling Wang, Huan Wang, Jing Luo, Ting Xie, Gil Mor, Aihua Liao.  (2022)  Decorin promotes decidual M1-like macrophage polarization via mitochondrial dysfunction resulting in recurrent pregnancy loss.  Theranostics,  12  (17): ( 7216–7236).  [PMID:36438479]

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