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Adenosine 5'-Triphosphate Disodium Salt Hydrate - 99%,for cell culture, high purity , CAS No.34369-07-8

15 Citations
Item Number
A100885
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A100885-200mg
200mg
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$11.90
A100885-1g
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$45.90
A100885-5g
5g
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$142.90
A100885-25g
25g
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$641.90
A100885-100g
100g
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,049.90
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Purine Nucleotides

Basic Description

SynonymsAdenosine 5'-triphosphate disodium salt hydrate | disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate | MFCD00150755 | Adenosine-5'-triphosphate disodium salt
Specifications & Purityfor cell culture, ≥99%
Biochemical and Physiological MechanismsP2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Gradefor cell culture
Product Description

application：

Adenosine 5′-triphosphate disodium salt hydrate has been used:

as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites

in inflammasome activation assays in bone marrow derived macrophages

for the stimulation of macrophages

in nucleotide synthesis


product description：

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Names and Identifiers

Pubchem Sid488199328
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488199328
IUPAC Name disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate
INCHI InChI=1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChi Key NTBQNWBHIXNPRU-MSQVLRTGSA-L
Canonical SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]
WGK Germany 3
Alternate CAS 987-65-5
PubChem CID 16218877
Molecular Weight 551.14(anhydrous basis)

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

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17 results found

Lot NumberCertificate TypeDateItem
D2428071Certificate of AnalysisApr 01, 2024 A100885
L2321365Certificate of AnalysisDec 27, 2023 A100885
L2321359Certificate of AnalysisDec 25, 2023 A100885
H2318227Certificate of AnalysisAug 10, 2023 A100885
H2318226Certificate of AnalysisAug 10, 2023 A100885
B2321081Certificate of AnalysisFeb 27, 2023 A100885
F2213183Certificate of AnalysisMay 14, 2022 A100885
F2213184Certificate of AnalysisMay 14, 2022 A100885
F2213188Certificate of AnalysisMay 14, 2022 A100885
G2226051Certificate of AnalysisMay 14, 2022 A100885
G2226053Certificate of AnalysisMay 14, 2022 A100885
G2226054Certificate of AnalysisMay 14, 2022 A100885
C2207022Certificate of AnalysisFeb 24, 2022 A100885
C2207020Certificate of AnalysisFeb 24, 2022 A100885
B2321074Certificate of AnalysisFeb 24, 2022 A100885
C1826128Certificate of AnalysisJan 18, 2022 A100885
C1826129Certificate of AnalysisJan 11, 2022 A100885

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Chemical and Physical Properties

SolubilitySoluble in water.
Sensitivitylight & heat sensitive,Hygroscopic
Specific Rotation[α]-19° (C=3,H2O)

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 155

Related Documents

 SDS

 Specification Sheet

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Citations of This Product

How to Cite Aladdin Scientific Products?
1. Chunxia Gan, Titi Liu, Xiaorong Jia, Xueqin Huang, Xiangdong Qin, Xuanjun Wang, Jun Sheng, Huanhuan Xu.  (2023)  ATP supplementation suppresses UVB-induced photoaging in HaCaT cells via upregulation of expression of SIRT3 and SOD2.  SKIN RESEARCH AND TECHNOLOGY,  29  (3): (e13303).  [PMID:36973992] [10.1111/srt.13303]
2. Qiuyang Huang, Xiaoling Zang, Zhiwei Zhang, Hang Yu, Baoyan Ding, Zhuangzhuang Li, Simin Cheng, Xin Zhang, Mustafa R.K. Ali, Xue Qiu, Zhihua Lv.  (2023)  Study on endogenous inhibitors against PD-L1: cAMP as a potential candidate.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  230  (123266).  [PMID:36646351] [10.1016/j.ijbiomac.2023.123266]
3. Yi Xia, Wu Jianfang, Jiang He, Zhao Yan, Mei Jun.  (2022)  Kinase expression enhances phenolic aldehydes conversion and ethanol fermentability of Zymomonas mobilis.  BIOPROCESS AND BIOSYSTEMS ENGINEERING,  45  (8): (1319-1329).  [PMID:35786774] [10.1007/s00449-022-02747-3]
4. Jia Xu, Habib Khan, Li Yang.  (2021)  Hydrogel Paper-Based Analytical Devices: Separation-Free In Situ Assay of Small-Molecule Targets in Whole Blood.  ANALYTICAL CHEMISTRY,  93  (44): (14755–14763).  [PMID:34709797] [10.1021/acs.analchem.1c03347]
5. Xueyang Jin, Ming Zhang, Jinghui Lu, Ximeng Duan, Jinyao Chen, Yue Liu, Wenqiang Chang, Hongxiang Lou.  (2021)  Hinokitiol chelates intracellular iron to retard fungal growth by disturbing mitochondrial respiration.  Journal of Advanced Research,  34  (65).  [PMID:35024181] [10.1016/j.jare.2021.06.016]
6. Zhao Yan, Wang Qibin, Yan Shan, Zhou Jun, Huang Liangyong, Zhu Haitao, Ye Fang, Zhang Yonghong, Chen Lin, Chen Li, Zheng Tao.  (2021)  Bletilla striata Polysaccharide Promotes Diabetic Wound Healing Through Inhibition of the NLRP3 Inflammasome.  Frontiers in Pharmacology,  12  (937).  [PMID:33981238] [10.3389/fphar.2021.659215]
7. Mei He, Ma Yange, Wu Huimin, Wang Xuedong.  (2021)  Fluorescent and visual assay of H2O2 and glucose based on a highly sensitive copper nanoclusters-Ce(III) fluoroprobe.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  413  (8): (2135-2146).  [PMID:33511458] [10.1007/s00216-021-03181-2]
8. Xiaofang Jiang, Jing Hu, Yajun Zhang, Xiaoliang Zeng, Zhou Long.  (2020)  Fast synthesis of bimetallic metal-organic frameworks based on dielectric barrier discharge for analytical atomic spectrometry and ratiometric fluorescent sensing.  MICROCHEMICAL JOURNAL,  159  (105417).  [PMID:] [10.1016/j.microc.2020.105417]
9. Fangfang Cao, Yan Zhang, Yuhuan Sun, Zhenzhen Wang, Lu Zhang, Yanyan Huang, Chaoqun Liu, Zhen Liu, Jinsong Ren, Xiaogang Qu.  (2018)  Ultrasmall Nanozymes Isolated within Porous Carbonaceous Frameworks for Synergistic Cancer Therapy: Enhanced Oxidative Damage and Reduced Energy Supply.  CHEMISTRY OF MATERIALS,  30  (21): (7831–7839).  [PMID:] [10.1021/acs.chemmater.8b03348]
10. Su Yiping, Cui Mingfang, Zhu Jianhua, Wu Yayu, Wei Yaping, Bian Shicong.  (2018)  A facile synthesis of nanosheet-structured barium carbonate spheres with a superior adsorption capacity for Cr(VI) removal.  JOURNAL OF MATERIALS SCIENCE,  53  (6): (4078-4088).  [PMID:] [10.1007/s10853-017-1861-4]
11. Mengke Wang, Lei Wang, Qing Liu, Xingguang Su.  (2018)  A fluorescence sensor for protein kinase activity detection based on gold nanoparticles/copper nanoclusters system.  SENSORS AND ACTUATORS B-CHEMICAL,  256  (691).  [PMID:] [10.1016/j.snb.2017.09.213]
12. Lingzhi Zhao, Liu Zhao, Yanqing Miao, Chunye Liu, Chenxiao Zhang.  (2016)  Construction of a Turn Off-On-Off Fluorescent System Based on Competitive Coordination of Cu2+ between 6,7-Dihydroxycoumarin and Pyrophosphate Ion for Sensitive Assay of Pyrophosphatase Activity.  Journal of Analytical Methods in Chemistry,  2016  (4306838).  [PMID:27766179] [10.1155/2016/4306838]
13. Jian Sun, Bin Wang, Xue Zhao, Zong-Jun Li, Xiurong Yang.  (2016)  Fluorescent and Colorimetric Dual-Readout Assay for Inorganic Pyrophosphatase with Cu2+-Triggered Oxidation of o-Phenylenediamine.  ANALYTICAL CHEMISTRY,  88  (2): (1355–1361).  [PMID:26703206] [10.1021/acs.analchem.5b03848]
14. Yongheng Yin, Jiahui Wang, Shengtao Jiang, Xin Yang, Xuya Zhang, Ying Cao, Li Cao, Hong Wu.  (2015)  Novel composite membranes based on sulfonated poly(ether ether ketone) and adenosine triphosphate for enhanced proton conduction.  RSC Advances,  5  (92): (75434-75441).  [PMID:] [10.1039/C5RA14143E]
15. Zhaosheng Qian, Lujing Chai, Cong Tang, Yuanyuan Huang, Jianrong Chen, Hui Feng.  (2015)  Carbon Quantum Dots-Based Recyclable Real-Time Fluorescence Assay for Alkaline Phosphatase with Adenosine Triphosphate as Substrate.  ANALYTICAL CHEMISTRY,  87  (5): (2966–2973).  [PMID:25642736] [10.1021/ac504519b]

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