Adenosine 5'-Triphosphate Disodium Salt Hydrate - 99%,for cell culture, high purity , CAS No.34369-07-8

4 Citations
Item Number
A100885
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A100885-200mg
200mg
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1g
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A100885-5g
5g
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A100885-25g
25g
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100g
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Production requires sourcing of materials. We appreciate your patience and understanding.
$2,049.90
View related series
Purine Nucleotides

Basic Description

Synonyms34369-07-8 | ATP disodium salt | Adenosine 5'-triphosphate disodium salt hydrate | ATP disodium salt hydrate | disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate | MFCD0
Specifications & Purityfor cell culture, ≥99%
Biochemical and Physiological MechanismsP2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
Storage TempStore at -20°C,Argon charged
Shipped InIce chest + Ice pads
Gradefor cell culture
Product Description

application:

Adenosine 5′-triphosphate disodium salt hydrate has been used:

as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites

in inflammasome activation assays in bone marrow derived macrophages

for the stimulation of macrophages

in nucleotide synthesis


product description:

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Names and Identifiers

Pubchem Sid488199328
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488199328
IUPAC Name disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate
INCHI InChI=1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChi Key NTBQNWBHIXNPRU-MSQVLRTGSA-L
Canonical SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]
Isomeric SMILES C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]
WGK Germany 3
Alternate CAS 987-65-5
PubChem CID 16218877
Molecular Weight 551.14(anhydrous basis)

Certificates

Certificate of Analysis(COA)

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17 results found

Lot NumberCertificate TypeDateItem
D2428071Certificate of AnalysisApr 01, 2024 A100885
L2321365Certificate of AnalysisDec 27, 2023 A100885
L2321359Certificate of AnalysisDec 25, 2023 A100885
H2318227Certificate of AnalysisAug 10, 2023 A100885
H2318226Certificate of AnalysisAug 10, 2023 A100885
B2321081Certificate of AnalysisFeb 27, 2023 A100885
F2213183Certificate of AnalysisMay 14, 2022 A100885
F2213184Certificate of AnalysisMay 14, 2022 A100885
F2213188Certificate of AnalysisMay 14, 2022 A100885
G2226051Certificate of AnalysisMay 14, 2022 A100885
G2226053Certificate of AnalysisMay 14, 2022 A100885
G2226054Certificate of AnalysisMay 14, 2022 A100885
C2207022Certificate of AnalysisFeb 24, 2022 A100885
C2207020Certificate of AnalysisFeb 24, 2022 A100885
B2321074Certificate of AnalysisFeb 24, 2022 A100885
C1826128Certificate of AnalysisJan 18, 2022 A100885
C1826129Certificate of AnalysisJan 11, 2022 A100885

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Chemical and Physical Properties

SolubilitySoluble in water.
Sensitivitylight & heat sensitive,Hygroscopic
Specific Rotation[α]-19° (C=3,H2O)

Safety and Hazards(GHS)

WGK Germany 3
Merck Index 155

Related Documents

Alternative Products

Citations of This Product

1. Chunxia Gan, Titi Liu, Xiaorong Jia, Xueqin Huang, Xiangdong Qin, Xuanjun Wang, Jun Sheng, Huanhuan Xu.  (2023)  ATP supplementation suppresses UVB-induced photoaging in HaCaT cells via upregulation of expression of SIRT3 and SOD2.  SKIN RESEARCH AND TECHNOLOGY,  29  (3): (e13303).  [PMID:36973992]
2. Qiuyang Huang, Xiaoling Zang, Zhiwei Zhang, Hang Yu, Baoyan Ding, Zhuangzhuang Li, Simin Cheng, Xin Zhang, Mustafa R.K. Ali, Xue Qiu, Zhihua Lv.  (2023)  Study on endogenous inhibitors against PD-L1: cAMP as a potential candidate.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  230  (123266).  [PMID:36646351]
3. Yi Xia, Wu Jianfang, Jiang He, Zhao Yan, Mei Jun.  (2022)  Kinase expression enhances phenolic aldehydes conversion and ethanol fermentability of Zymomonas mobilis.  BIOPROCESS AND BIOSYSTEMS ENGINEERING,  45  (8): (1319-1329).  [PMID:35786774]
4. Jia Xu, Habib Khan, Li Yang.  (2021)  Hydrogel Paper-Based Analytical Devices: Separation-Free In Situ Assay of Small-Molecule Targets in Whole Blood.  ANALYTICAL CHEMISTRY,  93  (44): (14755–14763).  [PMID:34709797]

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52. Qiuyang Huang, Xiaoling Zang, Zhiwei Zhang, Hang Yu, Baoyan Ding, Zhuangzhuang Li, Simin Cheng, Xin Zhang, Mustafa R.K. Ali, Xue Qiu, Zhihua Lv.  (2023)  Study on endogenous inhibitors against PD-L1: cAMP as a potential candidate.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,  230  (123266).  [PMID:36646351]
53. Yi Xia, Wu Jianfang, Jiang He, Zhao Yan, Mei Jun.  (2022)  Kinase expression enhances phenolic aldehydes conversion and ethanol fermentability of Zymomonas mobilis.  BIOPROCESS AND BIOSYSTEMS ENGINEERING,  45  (8): (1319-1329).  [PMID:35786774]
54. Jia Xu, Habib Khan, Li Yang.  (2021)  Hydrogel Paper-Based Analytical Devices: Separation-Free In Situ Assay of Small-Molecule Targets in Whole Blood.  ANALYTICAL CHEMISTRY,  93  (44): (14755–14763).  [PMID:34709797]

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