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Adipic acid dihydrazide - >99.0%(HPLC), high purity , CAS No.1071-93-8
Basic Description Synonyms Adipic dihydrazide|1071-93-8|Adipic acid dihydrazide|Adipohydrazide|Hexanedihydrazide|Hexanedioic acid, dihydrazide|Adipic acid, dihydrazide|Adipoyldihydrazine|adipoyl dihydrazide|VK98I9YW5M|DTXSID0044361|Hexanedioic acid, 1,6-dihydrazide|NSC-3378|NSC-295 Specifications & Purity ≥99%(HPLC) Storage Temp Store at -20°C,Argon charged Shipped In Ice chest + Ice pads Product Description Homobifunctional cross-linking reagent that is specific for aldehydes resulting in relatively stable hydrazone linkages. This is commonly used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines. Note that the hydrazone bond may be stabilized by selective reduction using, for example, sodium cyanoborohydride.
Names and Identifiers Pubchem Sid 488183736 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488183736 IUPAC Name hexanedihydrazide INCHI InChI=1S/C6H14N4O2/c7-9-5(11)3-1-2-4-6(12)10-8/h1-4,7-8H2,(H,9,11)(H,10,12) InChi Key IBVAQQYNSHJXBV-UHFFFAOYSA-N Canonical SMILES C(CCC(=O)NN)CC(=O)NN Isomeric SMILES C(CCC(=O)NN)CC(=O)NN WGK Germany 3 RTECS AV1400000 PubChem CID 66117 Molecular Weight 174.2 Beilstein 973863 Reaxy-Rn 973863
Chemical and Physical Properties Solubility Soluble in water, alcohol and acetone. Sensitivity Air Sensitive Flash Point(°F) 302.0 °F Flash Point(°C) 150°C Melt Point(°C) 180-182°C
Safety and Hazards(GHS) Pictogram(s) GHS09 Signal Warning Hazard Statements H411: Toxic to aquatic life with long lasting effects
H317: May cause an allergic skin reaction
Precautionary Statements P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: wash with plenty of water.
P321: Specific treatment (see ... on this label).
P501: Dispose of contents/container to ...
P272: Contaminated work clothing should not be allowed out of the workplace.
P333+P313: IF SKIN irritation or rash occurs: Get medical advice/attention.
P362+P364: Take off contaminated clothing and wash it before reuse.
P391: Collect spillage.
WGK Germany 3 RTECS AV1400000 Reaxy-Rn 973863
References 1. Heli Cheng , Zhen Fan , Zhenyu Wang , Zejiang Guo , Jungang Jiang , Yimin Xie. (2023) Highly stretchable, fast self-healing nanocellulose hydrogel combining borate ester bonds and acylhydrazone bonds. International Journal of Biological Macromolecules, 245: (6): (125471). [PMID:
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