Adiponectin receptor agonist (K D values are 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively). AMPK and PPARα signaling activator. Shows antiobesogenic, antidiabetic and cardioprotective effects in vivo. Orally active.
Storage Temp
Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Associated Targets(Human)
ADIPOR1TbioAdiponectin receptor protein 1 (1 Activities)
1.Wang YT et al.. (2019) Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration.. Am J Physiol Cell Physiol, 317 (5):(C1034-C1047). [PMID:31483704]
2.Tarkhnishvili A et al.. (2022) Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice.. J Lipid Atheroscler, 11 (2):(161-177). [PMID:35656151]
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H2205637