Adenosine diphosphate (ADP) is a nucleoside diphosphate that plays a critical role in energy transfer reactions. ADP is produced from adenosine triphosphate (ATP) via the action of ATPases. ADP also plays a critical role in platelet function. ADP, stored in platelet-dense granules, is released upon platelet activation where it acts on purinergic receptors to mediate intracellular signaling and platelet aggregation. ADP is a key agonist involved in thrombosis and hemostasis.
1.Kuo-Chieh Liao,Christina F Sandall,David A Carlson,Annegret Ulke-Lemée,Jaye M Platnich,Philip F Hughes,Daniel A Muruve,Timothy A J Haystead,Justin A MacDonald. (2019-01-15) Application of immobilized ATP to the study of NLRP inflammasomes.. Archives of biochemistry and biophysics, 670 (104-115). [PMID:30641048]
2.Peipei Jin,Liansheng Wang,Rui Sha,Liu Liu,Jieying Qian,Nestor Ishimwe,Wenbin Zhang,Jing Qian,Yunjiao Zhang,Longping Wen. (2021-01-28) A blood circulation-prolonging peptide anchored biomimetic phage-platelet hybrid nanoparticle system for prolonged blood circulation and optimized anti-bacterial performance.. Theranostics, 11 ((5)):(2278-2296). [PMID:33500725]
3.Sophie Hallakou-Bozec,Micheline Kergoat,Pascale Fouqueray,Sébastien Bolze,David E Moller. (2021-02-20) Imeglimin amplifies glucose-stimulated insulin release from diabetic islets via a distinct mechanism of action.. PloS one, 16 ((2)):(e0241651-e0241651). [PMID:33606677]
4.Jianmin Zhang,Jia Yang,Huaishan Wang,Omar Sherbini,Matthew J Keuss,George Ke Umanah,Emily Ling-Lin Pai,Zhikai Chi,Kaisa Ma Paldanius,Wei He,Hong Wang,Shaida A Andrabi,Ted M Dawson,Valina L Dawson. (2018-04-17) The AAA\u2009+\u2009ATPase Thorase is neuroprotective against ischemic injury.. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 39 ((9)):(1836-1848). [PMID:29658368]
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