AER-271 - 98%, high purity , CAS No.634913-39-6

Item Number

A649710

Grouped product items
SKU	Size	Availability	Price
A649710-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$56.90
A649710-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$96.90
A649710-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$193.90
A649710-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$308.90
A649710-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$493.90

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Basic Description

Synonyms	2-(3,5-bis(Trifluoromethyl)phenylcarbamoyl)-4-chlorophenyl dihydrogen phosphate \| AER-270 phosphate \| AER-270 precursor \| AER-270 prodrug \| IMD-0354 phosphate \| IMD-0354 precursor \| IMD-0354 prodrug \| N-[3,5-bis(Trifluoromethyl)phenyl]-5-chloro-2-(phosph
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	AER-271 is an inhibitor of aquaporin-4. In Vivo：Treatment with AER-271 ameliorated early cerebral edema measured at 3 h after CA vs vehicle treated rats. This treatment also attenuated early NDS. In contrast to rats treated with vehicle after CA, rats treated with AER-271 did not develop significant neuronal death or neuroinflammation as compared to sham. IC50& Target:Aquaporin-4 (AQP4)

Names and Identifiers

IUPAC Name	[2-[[3,5-bis(trifluoromethyl)phenyl]carbamoyl]-4-chlorophenyl] dihydrogen phosphate
INCHI	InChI=1S/C15H9ClF6NO5P/c16-9-1-2-12(28-29(25,26)27)11(6-9)13(24)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6H,(H,23,24)(H2,25,26,27)
InChi Key	WSHXPHFIHYXZKC-UHFFFAOYSA-N
Canonical SMILES	C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)OP(=O)(O)O
Isomeric SMILES	C1=CC(=C(C=C1Cl)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)OP(=O)(O)O
PubChem CID	10412080
MeSH Entry Terms	2-((3,5-Bis(trifluoromethyl) phenyl)carbamoyl)-4-chlorophenyl dihydrogen phosphate;AER-271
Molecular Weight	463.65

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
A2423107	Certificate of Analysis	Jan 13, 2024	A649710
A2423111	Certificate of Analysis	Jan 13, 2024	A649710
A2423112	Certificate of Analysis	Jan 13, 2024	A649710
A2423120	Certificate of Analysis	Jan 13, 2024	A649710
A2423121	Certificate of Analysis	Jan 13, 2024	A649710
A2423122	Certificate of Analysis	Jan 13, 2024	A649710
A2423123	Certificate of Analysis	Jan 13, 2024	A649710
A2423124	Certificate of Analysis	Jan 13, 2024	A649710
A2423135	Certificate of Analysis	Jan 13, 2024	A649710
A2423136	Certificate of Analysis	Jan 13, 2024	A649710

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Basic Description