118409-62-4|Tyrphostin AG 126|AG-126|AG 126|ag126|Tyrphostin AG126|alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile|2-(3-hydroxy-4-nitrobenzylidene)malononitrile|2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile|tyrphostin AG-126|Propanedinitrile,2-[(
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Tyrosine kinase inhibitor. Inhibits glucocorticoid induced COX-2 activity (IC 50 = 15 μM). Blocks lipopolysaccharide (LPS) induced TNFα synthesis and tyrosine phosphorylation of ERK2. Cell-permeable. Shows anti-inflammtory activity. Active in vivo .
Source
Synthetic
Storage Temp
Store at 2-8°C,Protected from light
Shipped In
Wet ice
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at Room Temperature. The product can be stored for up to 12 months.
H2223619