| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| A656154-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $106.90 |
| Specifications & Purity | 10mM in DMSO |
|---|---|
| Biochemical and Physiological Mechanisms | AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor. |
| Storage Temp | Store at -80°C |
| Shipped In | Ice chest + Ice pads |
| Product Description | AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor In Vitro AGL-2263 (5 μM, for 1 h followed by insulin treatment for 24 h) inhibits IR and insulin could still induce phosphorylation of AKT and ERK1/2 after the IR inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: Granulosa cells. Concentration: 5 μM. Incubation Time: For 1 h followed by insulin treatment for 24 h. Result: Insulin still induced phosphorylation of AKT and ERK1/2 after IR was inhibited by AGL2263. IC50& Target:Insulin receptor |
| Canonical SMILES | C1=CC2=C(C=C1C=C(C#N)C(=O)C3=CC(=C(C=C3)O)O)NC(=O)O2 |
|---|---|
| Molecular Weight | 322.27 |
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