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AGL-2263 - 10mM in DMSO, high purity , CAS No.638213-98-6(DMSO)

  • 10mM in DMSO
Item Number
A656154
Grouped product items
SKUSizeAvailabilityPrice Qty
A656154-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$106.90

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

AGL-2263 is an insulin receptor and insulin-like growth factor (IGF) receptor inhibitor

In Vitro

AGL-2263 (5 μM, for 1 h followed by insulin treatment for 24 h) inhibits IR and insulin could still induce phosphorylation of AKT and ERK1/2 after the IR inhibition. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: Granulosa cells. Concentration: 5 μM. Incubation Time: For 1 h followed by insulin treatment for 24 h. Result: Insulin still induced phosphorylation of AKT and ERK1/2 after IR was inhibited by AGL2263.

IC50& Target:Insulin receptor

Names and Identifiers

Canonical SMILES C1=CC2=C(C=C1C=C(C#N)C(=O)C3=CC(=C(C=C3)O)O)NC(=O)O2
Molecular Weight 322.27

Certificates

Certificate of Analysis(COA)

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