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AIDA - ≥98%(HPLC), high purity , CAS No.168560-79-0, Antagonist of mGlu 1 receptor
Potent and selective group I mGlu antagonist
Basic Description Synonyms AIDA|168560-79-0|UPF 523|1-Aminoindan-1,5-dicarboxylic acid|GNF-PF-1401|1-Amino-2,3-dihydro-1H-indene-1,5-dicarboxylic acid|UPF-523|1-amino-2,3-dihydroindene-1,5-dicarboxylic acid|1H-Indene-1,5-dicarboxylic acid, 1-amino-2,3-dihydro-|CHEMBL313938|UPF523;U Specifications & Purity Moligand™, ≥98%(HPLC) Biochemical and Physiological Mechanisms A relatively potent and selective antagonist of group I metabotropic glutamate receptors (mGlu1a), having no effect on group II (mGlu2) or group III (mGlu4) receptors expressed individually in baby hamster kidney cells. Has no effect on ionotropic glutama Storage Temp Room temperature Shipped In Normal Grade Moligand™ Action Type ANTAGONIST Mechanism of action Antagonist of mGlu 1 receptor
Names and Identifiers IUPAC Name 1-amino-2,3-dihydroindene-1,5-dicarboxylic acid INCHI InChI=1S/C11H11NO4/c12-11(10(15)16)4-3-6-5-7(9(13)14)1-2-8(6)11/h1-2,5H,3-4,12H2,(H,13,14)(H,15,16) InChi Key LSTPKMWNRWCNLS-UHFFFAOYSA-N Canonical SMILES C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N Isomeric SMILES C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N PubChem CID 2071 Molecular Weight 221.21
Chemical and Physical Properties Solubility Solvent:1.1eq. NaOH, Max Conc. mg/mL: 22.12, Max Conc. mM: 100
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