AKT-IN-3 - 99%, high purity , CAS No.2374740-21-1

Item Number

A647070

• Specifications & Purity: 99%
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

AKT-IN-3 (compound E22) is a potent, orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1 , Akt2 and Akt3 , respectively. AKT-IN-3 (compound E22) also exhibits good inhibitory activity against other AGC family kinases, such as PKA , PKC , ROCK1 , RSK1 , P70S6K , and SGK . AKT-IN-3 (compound E22) induces apoptosis and inhibits metastasis of cancer cells

Form:Solid

IC50& Target:Akt1 1.4 nM (IC 50 ) Akt2 1.2 nM (IC 50 ) Akt3 1.7 nM (IC 50 ) PKA 0.3 nM (IC 50 ) P70S6K 8.9 (IC 50 )