Discover Akt Inhibitor XII, Isozyme-Selective, Akti-2 by Aladdin Scientific in ≥97% for only $456.90. Available - in Ligands at Aladdin Scientific. a cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity Tags: .
Basic Description
Specifications & Purity
≥97%
Storage Temp
Store at 2-8°C
Shipped In
Wet ice
Product Description
A cell-permeable Akti-1/2- (sc-202048) derived allosteric inhibitor pair (1:1 regioisomeric mixture) with much improved aqueous solubility (10 mg/ml in a pH 7.4 saline) and Akt2 selectivity (IC|50|= 805 nM for Akt2, >10 µM for Akt1/3, and >50 µM for PKA/PKC/SGK). The inhibition is PH domain-dependent and non-competitive with ATP. Akt Inhibitor XII, Isozyme-Selective, Akti-2is a cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity