AKT Kinase Inhibitor - 99%, high purity , CAS No.842148-40-7

Item Number

A648039

• Synonyms: AKT Kinase Inhibitor|842148-40-7|3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethylimidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol|3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol|CHEMBL5235
• Specifications & Purity: ≥99%
• Biochemical and Physiological Mechanisms: AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.
• Storage Temp: Store at -20°C
• Shipped In: Ice chest + Ice pads

Product Description

AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.

In Vitro

The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid