AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Product Description
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity.
In Vitro
The effect of selective inhibition of Akt in proliferating cells expressing Trop-2 is studied. Akt inhibition, either by silencing or with specific drugs, induces a marked decrease in cell proliferation in cells expressing Trop-2, in a dose-dependent fashion. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Trop-2 expressing tumors subcutaneously injected in animal models show a striking reduction of growth following treatment with specific drugs that inhibit Akt activity. Therefore Akt has a central functional role in mediating the Trop-2-dependent growth stimulus . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Associated Targets(Human)
ROCK1TclinRho-associated protein kinase 1 (1 Activities)
