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Storage Temp | Store at -20°C |
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Shipped In | Ice chest + Ice pads |
Product Description | Product introduction: Amine-PEG4-Desthiobiotin is a pegylated amine compound whose biotin-like group is elutable from streptavidin, making it ideal for carbodiimide (EDC) conjugation to carboxylates for labeling and purification. Features of EZ-Link Amine-PEG4-Desthiobiotin, No-Weigh Format: • Desthiobiotin—analog of biotin allows easy elution from streptavidin, an ideal feature for affinity purification applications • Amine-activated—primary amine can be crosslinked to proteins and material surfaces using EDC and other crosslinkers • Pegylated—polyethylene glycol (PEG) groups in spacer arm enhances water solubility of biotinylated molecules This desthiobiotin compound is an amine-modified analog of biotin that contains a 4-unit polyethylene glycol (PEG) spacer arm. Desthiobiotinylation is accomplished by conjugating the primary amine to carboxyl groups on surface materials, peptides or proteins using the carbodiimide crosslinker . Carboxyl groups (-COOH) occur in aspartate or glutamate residues and the carboxy-terminus of polypeptides. When activated with NHS-ester Chemistry). • Spacer:Pegylated,28.8 Å • Labeling Method:Chemical Labeling • Cell Permeability:Cell-Impermeant |
Reactivity | Aldehyde,Carboxylic Acid,Ketone |
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Solubility | Water |
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