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ALK inhibitor 1 - 99%, high purity , CAS No.761436-81-1

  • ≥99%
Item Number
A648603
Grouped product items
SKUSizeAvailabilityPrice Qty
A648603-2mg
2mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$121.90
A648603-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$240.90
A648603-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$360.90
A648603-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$720.90
A648603-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,200.90

Basic Description

SynonymsALK inhibitor 1|761436-81-1|2-[[5-bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide|SCHEMBL282266|DTXSID30647725|BCP28167|AKOS030526894|CS-0788|NCGC00378862-01|HY-15357|MS-30201|A14987|F84839|A923189|2-(
Specifications & Purity99%
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Product Description

ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 ( TSSK2 ; IC 50 =31 nM) and focal adhesion kinase ( FAK ; IC 50 =2 nM).

In Vitro

ALK inhibitor 1 (compound 17) inhibits IGF-1R with an IC 50 of 90 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Names and Identifiers

IUPAC Name 2-[[5-bromo-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide
INCHI InChI=1S/C23H28BrN7O3S/c1-25-35(32,33)21-7-5-4-6-19(21)27-22-17(24)15-26-23(29-22)28-18-9-8-16(14-20(18)34-3)31-12-10-30(2)11-13-31/h4-9,14-15,25H,10-13H2,1-3H3,(H2,26,27,28,29)
InChi Key FTSDLONCFCQDGA-UHFFFAOYSA-N
Canonical SMILES CNS(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Br)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
Isomeric SMILES CNS(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Br)NC3=C(C=C(C=C3)N4CCN(CC4)C)OC
PubChem CID 24857689
Molecular Weight 562.48

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilityDMSO : ≥ 100 mg/mL (177.78 mM) 1M HCl : 100 mg/mL (177.78 mM; ultrasonic and adjust pH to 1 with HCl)

Related Documents

Solution Calculators