ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 ( TSSK2 ; IC 50 =31 nM) and focal adhesion kinase ( FAK ; IC 50 =2 nM).
In Vitro
ALK inhibitor 1 (compound 17) inhibits IGF-1R with an IC 50 of 90 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
