ALK2-IN-1 - 98%, high purity , CAS No.2141955-96-4, Inhibitor of activin A receptor type 1

Item Number

A412609

Grouped product items
SKU	Size	Availability	Price
A412609-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$217.90
A412609-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$329.90
A412609-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$699.90
A412609-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$929.90
A412609-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,259.90

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Basic Description

Synonyms	fidrisertib\|2141955-96-4\|BLU-782\|ALK2-IN-1\|BLU782\|(R)-Tetrahydrofuran-3-yl 4-(6-(5-(4-ethoxy-1-isopropylpiperidin-4-yl)pyridin-2-yl)pyrrolo[1,2-b]pyridazin-4-yl)piperazine-1-carboxylate\|KF4ZI0CJ7M\|IPN60130\|IPN-60130\|(R)-Tetrahydrofuran-3-yl4-(6-(5-(4-etho
Specifications & Purity	98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Action Type	INHIBITOR
Mechanism of action	Inhibitor of activin A receptor type 1
Product Description	Information ALK2-IN-1 (BLU-782) is a potent and selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM.

Names and Identifiers

IUPAC Name	[(3R)-oxolan-3-yl] 4-[6-[5-(4-ethoxy-1-propan-2-ylpiperidin-4-yl)pyridin-2-yl]pyrrolo[1,2-b]pyridazin-4-yl]piperazine-1-carboxylate
INCHI	InChI=1S/C31H42N6O4/c1-4-40-31(9-12-34(13-10-31)23(2)3)25-5-6-27(32-20-25)24-19-29-28(7-11-33-37(29)21-24)35-14-16-36(17-15-35)30(38)41-26-8-18-39-22-26/h5-7,11,19-21,23,26H,4,8-10,12-18,22H2,1-3H3/t26-/m1/s1
InChi Key	SWVYYNLRVIYURK-AREMUKBSSA-N
Canonical SMILES	CCOC1(CCN(CC1)C(C)C)C2=CN=C(C=C2)C3=CN4C(=C3)C(=CC=N4)N5CCN(CC5)C(=O)OC6CCOC6
Isomeric SMILES	CCOC1(CCN(CC1)C(C)C)C2=CN=C(C=C2)C3=CN4C(=C3)C(=CC=N4)N5CCN(CC5)C(=O)O[C@@H]6CCOC6
PubChem CID	132026427
Molecular Weight	562.70

PubChem CID

CAS Registry No.

Certificates

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10 results found

Lot Number	Certificate Type	Date	Item
G2410195	Certificate of Analysis	Mar 28, 2024	A412609
G2410204	Certificate of Analysis	Mar 28, 2024	A412609
G2410262	Certificate of Analysis	Mar 28, 2024	A412609
G2410269	Certificate of Analysis	Mar 28, 2024	A412609
G2410270	Certificate of Analysis	Mar 28, 2024	A412609
G2410273	Certificate of Analysis	Mar 28, 2024	A412609
G2410275	Certificate of Analysis	Mar 28, 2024	A412609
G2410276	Certificate of Analysis	Mar 28, 2024	A412609
G2410277	Certificate of Analysis	Mar 28, 2024	A412609
G2410278	Certificate of Analysis	Mar 28, 2024	A412609

Safety and Hazards(GHS)

Signal	Warning
Hazard Statements	H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation H302:Harmful if swallowed
Precautionary Statements	P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P301+P312:IF SWALLOWED: call a POISON CENTER/doctor/... IF you feel unwell.

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Basic Description