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Aloin - 10mM in DMSO, high purity , CAS No.1415-73-2(DMSO)

  • 10mM in DMSO
Item Number
A408967
Grouped product items
SKUSizeAvailabilityPrice Qty
A408967-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$146.90

Tyrosinase Inhibitors

Basic Description

Specifications & Purity10mM in DMSO
Storage TempStore at -80°C
Shipped InIce chest + Ice pads
Product Description

Information

Aloin Aloin (Barbaloin, Barbalin), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.
In vitro

Aloin, a natural anthracycline from Aloe vera, is a tyrosinase inhibitor with inhibitory rates of 2mM. Aloin shows a pronounced antiproliferative effect at physiological concentration (IC50 = 97 μM), causes cell cycle arrest in the S phase and markedly increases HeLaS3 cell apoptosis (to 24%). Aloin causes a reduction in the proportion of cells undergoing mitosis by induction of apoptosis, inhibition of topo II alpha protein expression and downregulation of cyclin B1 protein expression in MCF-7 cell line.

In vivo


Cell Data

cell lines:HF1A3, HF4.9 and HF28RA cells

Concentrations:

Incubation Time:

Powder Purity:≥98%

Names and Identifiers

Canonical SMILES OCC1OC(C(O)C(O)C1O)C2C3=C(C(=CC=C3)O)C(=O)C4=C2C=C(CO)C=C4O
Molecular Weight 418.39

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolubility (25°C) In vitro DMSO: 177 mg/mL (199.94 mM); Water: 177 mg/mL (199.94 mM); Ethanol: 177 mg/mL (199.94 mM);

Related Documents

Solution Calculators